Padres vs. Astros Odds & Betting Predictions - April 19, 2025
Padres at Astros
12:10 am • SCHNStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 4.62 | 5-3 | |
![]() | ![]() | 6.66 | 2-2 |
Padres at Astros Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Padres 42-35 | +1.5 | +1.5-152 | o9-112 | +140 |
![]() Astros 45-33 | u9 | -1.5+126 | u9-112 | -173 |

Daikin ParkHouston
Padres vs. Astros Expert Picks

Top Shelf Action 🥃
Last 30d: 142-94-4 (+29.1u)
R.Gusto u15.5 Outs-175
1.14u
4.58% ev
YBK Picks.com
Last 30d: 28-23-4 (+3.4u)
HOU -1-115
1.74u

Top Shelf Action 🥃
Last 30d: 142-94-4 (+29.1u)
C.Walker o0.5 HR+440
0.2u
C.Walker o0.5 HR+420
0.2u
3.27% ev

Sir Lockselot
Last 30d: 34-59-0 (+2.1u)
F.Tatis o0.5 RBI+130
2u
🔑 Fernando Tatis 1+ RBI +130 (DraftKings) 2u
Nando is locked in this season. 14 RBI in in 18 GP. 2 mid pitchers going so I expect a lot of runs (so does Vegas with a 9.5 O/U. BetAlytics model loves this one too. 5 ⭐️ grade and a 52.8% expected win probability
Code LOCKSELOT for 25% off at BetAlytics
Join 👉🔗 https://www.betalytics.com/

Steak Friend
Last 30d: 82-105-0 (-34.5u)
HOU -152
1u

Top Shelf Action 🥃
Last 30d: 142-94-4 (+29.1u)
R.Gusto u4.5 Ks-155
0.84u
3.41% ev

Boomer Betz
Last 30d: 211-216-4 (+4.0u)
K.Hart u3.5 Ks-106
0.94u
#SO

Mjaybrod
Last 30d: 33-34-0 (+6.5u)
HOU -137
0.73u
Bring out the garbage cans

Anders
Last 30d: 5-4-1 (+3.0u)
HOU -1.5+155
1.55u
Love the price and fits my favorite MLB system

Sean Zerillo
Last 30d: 145-142-3 (+6.1u)
HOU -125 (F5)
0.25u
Bet to -140

Picks Office
Last 30d: 86-76-2 (+9.9u)
HOU -125
0.8u
Astros are undervalued here — Ryan Gusto owns a 3.00 ERA, 2.83 xERA, and elite 31.9% K rate. Hart? 5.40 ERA, just 17.4% Ks. Gusto’s walk rate just 6.4%, limits damage. Plus run values on all pitch types. Hard contact allowed under 45% — dude’s dialed in.
Houston lineup’s stacked — six starters with xwOBA north of .300, setting tone early. Yordan (.398) + Peña (.393) lead the charge. Average exit velocity above 90 mph, launch angle dialed for damage.
Home park helps slug — Minute Maid boosts their profile notably. Astros thrive at home — offense up 15%, best RISP avg in MLB this season.

Sean Zerillo
Last 30d: 145-142-3 (+6.1u)
Under 9-115
0.58u
Friday. Assuming roof closed. Bet to -115
HOU -120
0.42u
Friday. Flat to -130
Padres vs. Astros Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Padres vs. Astros Public Betting Percentages
Betting Trends
- Astros are 3-2 in their last 5 games.
- Astros are 1-4 in their last 5 games against the spread
- Astros are 19-19 in their road games against the spread
- The totals have gone OVER in 3 of Astros' last 5 games
- The totals have gone OVER in 16 of Astros' 40 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Padres Injury Updates

Astros Injuries
- Lance McCullersSP
Lance McCullers (foot) has been scratched Monday. Ryan Gusto will start for the Astros.
Out
- Taylor TrammellLF
Trammell is out with calf
Out
- Cristian JavierSP
Javier is out with elbow
Out
- Luis GarciaSP
Garcia is out with elbow
Out
- Pedro LeonRF
Leon is out with knee
Out
- J.P. FranceSP
France is out with shoulder
Out
- Hayden WesneskiRP
Wesneski is out with elbow
Out
- Spencer ArrighettiSP
Arrighetti is out with thumb
Out

Padres Injuries
- Joe MusgroveSP
Musgrove is out for season with elbow
Out for Season
- Yu DarvishSP
Darvish is out with elbow
Out
- Michael KingSP
Michael King (shoulder) has been scratched Saturday. Sean Reynolds will start for the Padres.
Out
- Matt WaldronSP
Waldron is out with hamstring
Out
Padres vs. Astros Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 79 | 5 | 2 | 5 | |
![]() | 20 | 2 | 1 | 0 | |
![]() | 20 | 1 | 1 | 1 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 1 | 0 | 0 |
![]() | 3-5 | 1 | 1 | 2 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 1 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 68 | 5 | 2 | 2 | |
![]() | 14 | 1 | 2 | 0 | |
![]() | 16 | 1 | 0 | 2 | |
![]() | 15 | 1 | 2 | 0 | |
![]() | 10 | 1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 3-4 | 1 | 0 | 1 |
![]() | 2-4 | 2 | 2 | 4 |
![]() | 0-0 | 0 | 0 | 0 |
Padres vs. Astros Odds Comparison
Could not load odds
Padres at Astros Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Padres 42-35 | o3.5-130 | u3.5+103 |
![]() Astros 45-33 | o4.5-120 | u4.5-108 |