Yankees vs. Red Sox Odds & Betting Predictions - April 22, 2026
Yankees at Red Sox
10:45 pm • MLB NetworkStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.15 | 4-3 | ||
![]() | 3.21 | 4-3 |
Yankees at Red Sox Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Yankees 52-42 | -1.5 | -1.5+125 | o7.5-107 | -132 |
Red Sox 44-48 | u7.5 | +1.5-154 | u7.5-116 | +112 |

Fenway ParkBoston
Yankees vs. Red Sox Expert Picks
OldSchool0909
Last 30d: 28-25-0 (+8.4u)
BOS +375 (Live)
1u
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
NYY -125 (F5)
0.8u
Anthony Dabbundo
Last 30d: 59-56-6 (+9.2u)
NYY -130
1u
Matt Trollo
Last 30d: 97-118-4 (-15.2u)
R.Suarez u4.5 Ks+120
0.6u
Has topped out at 8.3 SwStr% in 4 starts - 3 of first 5 in NYY LU < 12.5 K% v LHP since LY - Hitter leaning umpire.
Collin Whitchurch
Last 30d: 13-25-1 (-4.4u)
C.Wong To Record 2+ Total Bases Yes+176
0.13u
Frank Ammirante
Last 30d: 400-407-8 (-2.7u)
W.Contreras o0.5 HR+560
0.1u
Brian Bitler
Last 30d: 58-74-0 (-44.1u)
BOS +125
3u
Picks Office
Last 30d: 171-173-15 (-17.6u)
Under 8-120
0.83u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Doug Ziefel
Last 30d: 148-170-17 (+8.9u)
R.Suarez u5.5 Ks-137
0.5u
Top Shelf Action 🥃
Last 30d: 1-0-0 (+2.6u)
NYY -1.5+135
0.27u
#EV
Pinny +127
Circa +120
BM +122
BO +125
Frank Ammirante
Last 30d: 400-407-8 (-2.7u)
Under 8-118
1u
M.Fried o17.5 Outs-155
1u
R.Suarez o16.5 Outs-130
1.3u

Sean Zerillo
Last 30d: 124-129-6 (-6.5u)
NYY -140
0.5u
Bet to -150
Doug Ziefel
Last 30d: 148-170-17 (+8.9u)
BOS +125
0.4u
Yankees vs. Red Sox Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Yankees vs. Red Sox Public Betting Percentages
Betting Trends
- Red Sox are 5-0 in their last 5 games.
- Red Sox are 4-1 in their last 5 games against the spread
- Red Sox are 25-23 in their road games against the spread
- The totals have gone OVER in 3 of Red Sox' last 5 games
- The totals have gone OVER in 17 of Red Sox' 44 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Red Sox vs. Yankees Injury Updates

Red Sox Injuries
- Tanner HouckP
Houck is out with arm
Out
- Triston CasasIF
Casas is out with knee
Out
- Kutter CrawfordP
Crawford is out with wrist
Out

Yankees Injuries
- Clarke SchmidtP
Schmidt is out with elbow
Out
Yankees vs. Red Sox Box Score
Yankees Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 100 | 8 | 9 | 0 | |
![]() | 26 | 1 | 0 | 1 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-2 | 2 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 1 | 4 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Red Sox Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 71 | 4.2 | 4 | 4 | |
![]() | 11 | 1 | 2 | 0 | |
![]() | 41 | 3.1 | 3 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 3-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Yankees vs. Red Sox Odds Comparison
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Yankees at Red Sox Team Totals
MatchupOverUnder | ||
|---|---|---|
Yankees 52-42 | N/A | N/A |
Red Sox 44-48 | N/A | N/A |



























