The Athletics host the Houston Astros on April 4, 2026. First pitch from Sutter Health Park is scheduled for 4:05 p.m. EDT. The game will be broadcast on NBCS-CA.
The Astros are favored by -112 on the moneyline and by -1.5 on the run line. The Athletics are -104 on the moneyline and +1.5 on the run line. The total is set at 10 runs.
Find my MLB picks and Astros vs Athletics prediction below, as well as probable pitchers, weather report, and more.
Astros vs Athletics Prediction
- Astros vs Athletics Pick: Over 10 (-110 or Better)
My Astros vs Athletics best bet is on the Over. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Athletics Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +138 | 10 -104o / -118u | -112 |
| Athletics Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -166 | 10 -104o / -118u | -104 |
- Astros vs Athletics spread: Astros -1.5 (+138), Athletics +1.5 (-166)
- Astros vs Athletics over/under: 10 (-104 / -118)
- Astros vs Athletics moneyline: Astros -112, Athletics -104
Astros vs Athletics Pitchers
| Tatsuya Imai (RHP) | Stat | Luis Morales (RHP) |
|---|---|---|
| 0-0 | W-L | 0-1 |
| 0.0 | fWAR (FanGraphs) | -0.2 |
| 13.50 / 5.64 | ERA / xERA | 10.38 / 13.17 |
| 4.68 / 5.24 | FIP / xFIP | 11.26 / 5.32 |
| 2.63 | WHIP | 1.62 |
| 0.0% | K-BB% | 15% |
| 57.1% | GB% | 7.7% |
| 90 | Stuff+ | 85 |
| 100 | Location+ | 94 |
Astros vs Athletics MLB Betting Preview
Our own Sean Zerillo projects exactly 10.5 runs for Saturday's Astros-Athletics game, yet the consensus line is still sitting around 10. That means we're showing a 2% edge against the market on the Over.
As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
Astros vs Athletics Picks
Zerillo says we should bet the Over at 10 (-110) or better, so I'll do the same.
The Astros lineup is locked in, ranking second among MLB teams in wRC+ (132). The Athletics have slumped to start the season, but they still have one of the league's more dangerous lineups.
These are two brutal pitchers, and Sutter Health Park is an excellent run-scoring environment.
Pick: Over 10 (-110 or Better)
