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Yankees vs Diamondbacks Prediction, Pick, MLB Odds for Sunday, September 20

Yankees vs Diamondbacks Prediction, Pick, MLB Odds for Sunday, September 20 article feature image
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Matt Kartozian-Imagn Images. Pictured: Diamondbacks Corbin Burnes

The Arizona Diamondbacks host the New York Yankees on September 20, 2026. First pitch from Chase Field is scheduled for 4:10 p.m. ET. The game will be broadcast on YES.

The Yankees are favored by -115 on the moneyline and by -1.5 on the run line. The Diamondbacks are -105 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find our MLB picks and Yankees vs Diamondbacks prediction below, as well as probable pitchers, weather report, and more.


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Yankees vs Diamondbacks Prediction

  • Yankees vs Diamondbacks Pick: Diamondbacks ML (-105) / Under 8.5 (-115)

Our Yankees vs Diamondbacks best bets are Arizona to win outright and Under 8.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page, and download the Action Network app for more picks and analysis.


Yankees vs Diamondbacks Odds

Yankees Logo
Sunday, Sep 20
4:10 p.m. ET
YES
Diamondbacks Logo
Yankees Odds
SpreadTotalMoneyline
-1.5
+145
8.5
-105o / -115u
-115
Diamondbacks Odds
SpreadTotalMoneyline
+1.5
-180
8.5
-105o / -115u
-105
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo
  • Yankees vs Diamondbacks moneyline: Yankees -115, Diamondbacks -105
  • Yankees vs Diamondbacks over/under: 8.5 (-105o / -115u)
  • Yankees vs Diamondbacks spread: Yankees -1.5 (+145), Diamondbacks +1.5 (-180)

Yankees vs Diamondbacks Probable Pitchers

Will Warren (RHP, NYY)StatCorbin Burnes (RHP, ARI)
10-6W-L0-0
1.8fWAR (FanGraphs)0.0
3.89 / 4.42ERA / xERA5.87 / 3.74
4.07 / 3.78FIP / xFIP5.71 / 5.47
15.0K-BB%12.5
44.6GB%16.7
.309BABIP.227
103Stuff+95
106Location+104

Yankees vs Diamondbacks MLB Betting Preview

Sean Zerillo's projections show solid value on the Diamondbacks moneyline against the Yankees, with a 5.6% edge, and also on the total for this matchup, with 3.6% on the over.

If you want to dive deeper into this game, it'd be wise to check out BARTOLO, Zerillo's new PRO baseball tool that gives you access to all the input data he uses to project games every day.


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Yankees vs Diamondbacks Pick, Betting Analysis

BARTOLO projects the Yankees for 3.76 runs and the Diamondbacks for 4.06 today, which gives Arizona the edge to win outright and would also bring the total under the line.

Veteran SP Corbin Burnes will make only his third appearance this season for the Diamondbacks, but Zerillo projects him 53rd among all MLB starters, ahead of his opponent today, Will Warren.

However, the biggest advantage lies in the bullpen comparison, as BARTOLO has the Arizona reliever corps in the top spot in the majors this season, while New York ranks 20th.

Last night, the game ended with eight total runs, and with quality starters on both sides, the under is a nice second pick here.

Pick: Diamondbacks ML (-105) / Under 8.5 (-115)


Yankees vs Diamondbacks Weather


Get the latest coverage on MLB Weather.


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