The Los Angeles Dodgers host the San Francisco Giants on September 20, 2026. First pitch from UNIQLO Field at Dodger Stadium is scheduled for 4:10 p.m. EDT. The game will be broadcast on NBCS-BA.
The Dodgers are favored by -275 on the moneyline and by -1.5 on the run line. The Giants are +222 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Giants vs Dodgers prediction below, as well as probable pitchers, weather report, and more.
Giants vs Dodgers Prediction
- Giants vs Dodgers Pick: Mookie Betts Over 0.5 Home Runs (+470)
My Giants vs Dodgers best bet is on Betts to record 1+ home runs. Make sure to find the best odds by checking our live MLB odds page and be sure to download the Action Network app for more picks and analysis.
Giants vs Dodgers Odds
| Giants Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -125 | 8 -115o / -105u | +222 |
| Dodgers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +105 | 8 -115o / -105u | -275 |
- Giants vs Dodgers moneyline: Giants +222, Dodgers -275
- Giants vs Dodgers over/under: 8 (-115o / -105u)
- Giants vs Dodgers spread: Dodgers -1.5 (-125 ), Giants +1.5 (+105)
Giants vs Dodgers Probable Pitchers
| Matt Wilkinson | Stat | TBD |
|---|---|---|
| 1-3 | W-L | |
| 0.1 | fWAR (FanGraphs) | |
| 4.58 / 4.28 | ERA / xERA | |
| 5.13 / 5.33 | FIP / xFIP | |
| 9.9 | K-BB% | |
| 26.6 | GB% | |
| .230 | BABIP | |
| 86 | Stuff+ | |
| 108 | Location+ |
Giants vs Dodgers MLB Betting Preview
Giants vs Dodgers Pick, Betting Analysis
The Dodgers get a great spot today and the odds are a bit too high on the righties. We don't have a huge sample size on Matt Wilkinson, but he's allowed a massive 2.63 HR/9 to righties and he grades out as a great matchup for righty power. Mookie Betts is in a great spot today and I have the true odds around +420.
Pick: Mookie Betts Over 0.5 Home Runs (+470)
