Illinois vs. Duke Odds & Betting Predictions - September 6, 2025
Illinois at Duke
4:00 pm • ESPNIllinois at Duke Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Illinois 3-3 | -2.5 | -2.5-108 | o49-110 | -134 |
Duke 4-1 | u49.5 | +2.5-112 | u49-110 | +114 |

Brooks Field at Wallace Wade StadiumDurham
Illinois vs. Duke Expert Picks
Vegas Refund
Last 30d: 30-32-2 (-5.7u)
DUKE +2.5-105
1.05u
Collin Wilson
Last 30d: 75-57-2 (+6.8u)
DUKE +3-108
1.08u
Backing Darian Mensah v Illinois 3-3-5. Altmyer still breaking in new targets. Both teams flawless box scores in Week 1
Stuck 🚨
Last 30d: 68-67-1 (+1.9u)
DUKE +3-105
0.4u
Mike McNamara
Last 30d: 65-68-1 (+0.3u)
ILL -135
0.3u

Sean Zerillo
Last 30d: 115-109-6 (-0.6u)
Over 48.5-110
0.25u
Tyler Shoemaker
Last 30d: 63-83-1 (-18.8u)
DUKE +3-110
5.5u
Doug Ziefel
Last 30d: 351-390-8 (+13.9u)
ILL -3-110
0.5u
Ryan Minion
Last 30d: 214-252-5 (-43.2u)
ILL -130
$1.00
Sandy Plashkes
Last 30d: 98-92-2 (+32.2u)
DUKE +2.5-110
1.1u
Brian Bitler
Last 30d: 72-79-5 (-13.9u)
DUKE +2.5+105
3u
DUKE +3-108
3u
Big Bets On Campus (CFB)
Last 30d: 49-56-1 (-6.4u)
DUKE +3-105
1u
@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb
DUKE o23.5 Team Total-110
1u
@_Collin1 https://myaction.app/jBs4sSa5pWb
Mjaybrod
Last 30d: 52-80-1 (-29.4u)
DUKE +3-110
1u
Outright for the blue devils
Sir Lockselot
Last 30d: 11-35-0 (-11.9u)
DUKE +114
3u
📚Player Profit
🔑 Duke ML +114 (Player Profit) 3u
Mensah > Altmyer. Amazing value at home for what I think is the more talented team. Illinois struggles on the road generally. Go blue devils!
Code: sirlocks for 10% off every deposit at playerprofit.com
DeadPresPicks
Last 30d: 0-1-0 (-1.0u)
DUKE +3-110
0.75u
Illinois vs. Duke Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Illinois vs. Duke Public Betting Percentages
Betting Trends
- Duke are 4-1 in their last 5 games.
- Duke are 4-1 in their last 5 games against the spread
- Duke are 1-1 in their road games against the spread
- The totals have gone OVER in 3 of Duke' last 5 games
- The totals have gone OVER in 1 of Duke' 3 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
296
YDS
356
22/31
Comps/Atts
25/39
9.548387096774194
YPA
9.128205128205128
3/0
TDs/INTs
2/1
4/29
Sacks/Yards
2/7
Illinois vs. Duke Odds Comparison
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Illinois at Duke Team Totals
MatchupOverUnder | ||
|---|---|---|
Illinois 3-3 | N/A | N/A |
Duke 4-1 | N/A | N/A |






