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College Football Moneyline Underdogs: Week 5 Picks for Washington vs Ohio State, Iowa State vs Arizona

College Football Moneyline Underdogs: Week 5 Picks for Washington vs Ohio State, Iowa State vs Arizona article feature image
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Imagn Images. Pictured: Washington QB Demond Williams Jr. (left) and Arizona QB Noah Fifita (right).

Welcome to Week 5 of the college football season.

For the eighth straight season on our college football betting podcast, Big Bets on Campus, Collin Wilson and Stuckey pick their two favorite moneyline underdogs for each week's slate.

For Week 5 of the season, they're rolling with two Power 4 squads that are nearly touchdown underdogs.

We'll get things started Saturday afternoon up in Seattle and finish up with a Big 12 night game in the Heartland. If you're feeling lucky, a parlay of both pups pays out north of 9-1 at the time of writing.

Let's dive into our college football moneyline underdogs for Week 5.

  • 2018-24: 85-129, +15.91 Units
  • 2025: 4-4, +1.8 Units
  • Overall: 89-133, +17.71 Units
Playbook

College Football Moneyline Underdogs for Week 5

Collin Wilson: Washington ML +250 vs. Ohio State

Ohio State Logo
Saturday, Sep 27
3:30 p.m. ET
CBS
Washington Logo
Ohio State Odds
SpreadTotalMoneyline
-8
-110
51.5
-115o / -105u
-310
Washington Odds
SpreadTotalMoneyline
+8
-110
51.5
-115o / -105u
+250
Odds via bet365. Get up-to-the-minute NCAAF odds here.
bet365 Logo

I’m rolling with Washington against Ohio State. If this doesn’t work out, I’m gonna catch some heat, but hear me out.

Washington running back Jonah Coleman and quarterback Demond Williams Jr. are going to give Ohio State fits with their zone-read concepts. They boast a 73% Success Rate on inside zone runs, and they break off explosive plays on about one out of every three attempts on outside zone plays.

That spells trouble for Ohio State, especially since it's sitting at 118th in Defensive Stuff Rate.

Ohio State’s defensive line had a tough time holding down Texas on the ground, and I don’t see that changing against a disciplined Washington offense.

Fundamentals are key for this Ohio State defense. Defensive coordinator Matt Patricia might've picked up the win against Texas in Week 1, but there are concerns when looking deeper.

Caleb Downs had a 10% missed tackle rate last year, and that number has more than doubled to 21% this season. Plus, the Buckeyes rank 59th in PFF tackling grade as a unit.

When Washington has playmakers like Williams and Coleman hitting the second level and defenders missing tackles, the Huskies have a recipe to keep moving the chains.

I’m taking Washington here.


Stuckey: Arizona ML +200 vs. Iowa State

Arizona Logo
Saturday, Sept. 27
7 p.m. ET
ESPN
Iowa State Logo
Arizona Odds
SpreadTotalMoneyline
+6
-110
48.5
-110o / -110u
+200
Iowa State Odds
SpreadTotalMoneyline
-6
-110
48.5
-110o / -110u
-245
Odds via bet365. Get up-to-the-minute NCAAF odds here.
bet365 Logo

I like Arizona over Iowa State here.

Campbell's Law says every time Iowa State pulls off a win, it just looks worse the next day.

The Cyclones barely squeaked by Arkansas State, and then the Red Wolves got absolutely demolished by Kennesaw State. Kansas State has been a disaster. Even South Dakota looks downright terrible for what should be a solid FCS team.

Yes, Iowa State got a bye week, but guess what? Arizona had one, too.

Arizona quarterback Noah Fifita has also been playing really well for the Wildcats. He tends to hold onto the ball longer than most, but Iowa State’s defense hasn’t been able to generate any real pressure, so that doesn't matter nearly as much.

Then there’s the kicker situation for Iowa State. Both its kicker and kickoff specialist are injured, so a true freshman is expected to handle all those duties. That’s a wild card right there. It could mean better starting field position for Arizona and possibly missed kicks for Iowa State.

All things considered, I’m taking the Wildcats in this one.

Author Profile
About the Author

Stuckey is a senior betting analyst at Action Network, focusing on college football, college basketball, and the NFL. He hosts The Action Network Podcast and co-hosts the Big Bets on Campus podcast with Collin Wilson and Brett McMurphy. Stuckey was Action Network’s first content hire in 2017, helping launch their award-winning app, and continues to work closely with their development team. A CFA Charterholder, Stuckey has been betting since 2003 and has a background as a derivatives analyst in the financial industry. He holds an MBA from George Washington University.

Author Profile
About the Author

Collin is a senior writer for the Action Network, but serves in various roles behind the scenes as well. As someone who specializes in data visualization of probabilities, power ratings, and head-to-head matchups, Collin’s work within the college football space powers the Action Network’s PRO projections throughout the college football season, and has done so since the birth of the app in 2017. Collin contributes similarly to the college basketball vertical, and his passion for predictive analytics have led him to become a key force in finding betting edges in more niche markets such as professional wrestling and entertainment awards.

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