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Florida vs. Miami Picks, Odds, Parlay for College Football Week 4

Florida vs. Miami Picks, Odds, Parlay for College Football Week 4 article feature image
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Nathan Ray Seebeck-Imagn Images. Pictured: Malachi Toney.

The Florida Gators take on the Miami (FL) Hurricanes in Miami Gardens, Florida. Kickoff is set for 7:30 p.m. EDT on ABC.

Miami (FL) is favored by 7.5 points on the spread with a moneyline of -330. The total is set at 51 points.

Here’s my Florida vs. Miami (FL) predictions and college football picks for Saturday, September 20, 2025.

Quickslip

Florida vs. Miami Picks

  • Florida ML
  • Malachi Tooney Anytime Touchdown Scorer

Parlay Payout: +1200 (Bet365)

Florida vs Miami (FL) Odds

Florida Logo
Saturday, Sep 20
7:30 p.m. ET
ABC
Miami (FL) Logo
Florida Odds
SpreadTotalMoneyline
+7.5
-110
51
-110o / -110u
+250
Miami (FL) Odds
SpreadTotalMoneyline
-7.5
-110
51
-110o / -110u
-310
Odds via bet365. Get up-to-the-minute NCAAF odds here.
bet365 Logo
  • Florida vs Miami (FL) point spread: Miami (FL) -7.5 (-110), Florida +7.5 (-110)
  • Florida vs Miami (FL) over/under: 51 (-110o / -110u)
  • Florida vs Miami (FL) moneyline: Florida +250, Miami (FL) -310


Header First Logo

Florida ML

The Gators face another tough test Saturday night after back-to-back losses to ranked opponents, USF and LSU.

Billy Napier’s seat is heating up, as he’s now under .500 since taking over as head coach, making this game potentially season-altering for Florida.

Miami, meanwhile, is off to a hot start with wins over Notre Dame and USF.

Still, I see value with Florida on Saturday.

The Gators’ defense has been strong, holding LSU to 316 yards and allowing just 19 points per game through three contests.

Despite DJ Lagway’s five interceptions last week, Florida stayed competitive, and I expect him to bounce back in this prime-time matchup.


Header First Logo

Malachi Toney Anytime Touchdown Scorer

Malachi Toney has quickly become Miami quarterback Carson Beck’s favorite target, leading the Hurricanes with 18 receptions and 228 yards.

Florida has struggled to defend the slot, which sets up well for him in this matchup.

At +220, Toney offers substantial value to find the end zone against the Gators’ defense.


Florida vs. Miami Picks

  • Florida ML
  • Malachi Toney Anytime Touchdown Scorer

Parlay Payout: +1200 (Bet365)

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