The Cowboys visit the Lions tonight for Thursday Night Football at Ford Field. Kickoff for TNF is set for 8:15 p.m. ET on Prime Video.
For my Cowboys vs Lions anytime touchdown picks, I'm targeting George Pickens and Dak Prescott.
Continue below for my Cowboys vs Lions anytime touchdown preview for Thursday Night Football.
Cowboys vs Lions Anytime Touchdown Props
- George Pickens Anytime Touchdown (+125; FanDuel)
- Dak Prescott Anytime Touchdown (+725; BetMGM)
Cowboys vs Lions Anytime Touchdown Picks
George Pickens Anytime Touchdown (+125)

George Pickens has a prime matchup tonight.
The Lions play man coverage at the highest rate in the NFL and use single-high safety at a top-three rate. It works out perfectly because Pickens leads the Cowboys in yards per route run and TPRR against man coverages.
There’s a reason why Pickens is +125 to score — not only does he lead the Cowboys with 17 end-zone targets, he has an innate ability to beat man coverage.
I just can’t pass up on him onight.
Pick: George Pickens Anytime Touchdown (+125; FanDuel)
Dak Prescott Anytime Touchdown (+725)

Dak Prescott has two rushing touchdowns this season, and I think there’s some upside for him to run the ball more.
As mentioned above, Detroit plays man coverage at the highest rate in the NFL, and its use of single-high safety is at a top-three rate. This is rather inviting for quarterback scrambles and Prescott tends to save his legs for games later in the season.
Another factor is that there could be a higher chance of defensive pass interference (DPI) in the end zone that can lead for a potential tush push. Dallas leads the NFL in drawing DPIs (17) while the Lions rank bottom-five in allowing them (nine).
In a game with a ton of potential scoring, I like Prescott to call his own number here.
Pick: Dak Prescott Anytime Touchdown (+725; BetMGM)
Editor's Note: An anytime touchdown parlay is not the author's formal recommendation. These touchdown picks have value as straight bets.
















