USA Today Sports. Pictured: Daniel Jones, Tom Brady
- Can Tom Brady and the Patriots cover this massive Thursday Night Football spread?
- Our staff breaks down the betting odds for Giants at Patriots, complete with picks.
Giants at Patriots Betting Odds & Picks
- Patriots Spread: -17
- Giants Spread: +17
- Over/Under: 40.5
- Kickoff: 8:20 p.m. ET
- TV Channel: FOX/NFL Network
Odds as of Wednesday evening and via PointsBet, where Action Network users can access an exclusive promotion to get a 200% deposit match (deposit $50, bet with $150).
The Patriots have played as massive favorites three times season. They’ve covered twice. Now they’re -17 for their Thursday Night Football showdown against the Giants.
New York’s offense, meanwhile, is a shell of its former self with a cluster of injuries to key playmakers.
So how should you bet this large spread? What about the over/under?