NFL Playoffs Odds & Picks for Colts vs. Bills: Saturday’s Wild Card Edge To Bet Right Now

NFL Playoffs Odds & Picks for Colts vs. Bills: Saturday’s Wild Card Edge To Bet Right Now article feature image
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Bobby Ellis/Getty Images. Pictured: Jonathan Taylor, left, and Nyheim Hines of the Indianapolis Colts.

NFL Odds: Colts vs. Bills

Colts Odds+6.5
Bills Odds-6.5
Over/Under51
PRO ProjectionsBills -4 | O/U: 53.2
Time/Channel 1:05 p.m. ET/CBS
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The NFL's Wild Card Round is set, with six playoff matchups this weekend — three on Saturday and another trio of games Sunday.

In Saturday's first game, the Indianapolis Colts will travel to Buffalo to take on the Bills in a matchup that's also popping as one of the Wild Card Round's top betting edges, according to our NFL betting model.

Using our PRO Projections, let's look at the Colts vs. Bills edge to consider right now.

NFL Picks: Colts vs. Bills

*Odds as of Wednesday at 10:30 a.m. ET

We project the Colts vs. Bills spread to be Indianapolis +4, which translates to a 3.7% edge when compared to the current consensus line of +6.5.

This pick currently earns a B- grade from our PRO Projections feature, but, as always, be sure to visit our NFL Live Odds Page to not only lock in the best spread number, but to also shop for the most friendly vig.

Want access to all of our tools and software for a loaded weekend that includes the NFL Wild Card Playoffs, as well as Monday's Ohio State vs. Alabama national championship game?

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PRO Projections Pick: Colts +6.5

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