Week 4 NFL Odds: Spreads, Totals & Opening Lines For Every Game

Week 4 NFL Odds: Spreads, Totals & Opening Lines For Every Game article feature image
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Chris Graythen/Getty Images. Pictured: Tom Brady

Heading into Sunday Night Football, Week 3 favorites covered at a 8-5 rate while overs also hit at 8-5 rate.

With two primetime games left to play, oddsmakers have already released Week 4 opening lines. We’ve outlined all the posted spreads and totals available as of Sunday night below.

Week 4 NFL Odds: Spreads & Totals Odds


Odds as of Sunday night and via DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or see more offers and reviews for the best online sportsbooks.


Broncos at Jets Odds

  • Odds: Broncos -2.5 [Bet Now]
  • Total: 40 [Bet Now]
  • Time: 8:20 p.m. ET on Sept. 17
  • TV Channel: NFL Network

Cardinals at Panthers Odds

  • Odds: Cardinals -4 [Bet Now]
  • Total: 51.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Ravens at Washington Odds

  • Odds: Ravens -13.5 [Bet Now]
  • Total: N/A
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Browns at Cowboys Odds

  • Odds: Cowboys -5 [Bet Now]
  • Total: 55.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Colts at Bears Odds

  • Odds: Colts -2.5 [Bet Now]
  • Total: 44.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Jaguars at Bengals Odds

  • Odds: Bengals -3 [Bet Now]
  • Total: 44.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Chargers at Buccaneers Odds

  • Odds: Buccaneers -7 [Bet Now]
  • Total: 45.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS
2019-fantasy-football-cheat-sheets-rankings-projections-draft-kit
Michael Reaves/Getty Images. Pictured: Austin Ekeler

Vikings at Texans Odds

  • Odds: Texans -4 [Bet Now]
  • Total: 51.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Steelers at Titans

  • Odds: Titans -1.5 [Bet Now]
  • Total: 47.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Seahawks at Dolphins Odds

  • Odds: Seahawks -7 [Bet Now]
  • Total: 54.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Saints at Lions Odds

  • Odds: N/A
  • Total: N/A
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Check out our new NFL PRO Report, where we highlight factors that provide betting edges — like large wagers, historically profitable betting systems, model projections and expert picks — that when combined with sharp money can powerfully detail the smartest bets on a given slate.

Giants at Rams Odds

  • Odds: Rams -11.5 [Bet Now]
  • Total: 48 [Bet Now]
  • Time: 4:05 p.m. ET on Sept. 20
  • TV Channel: FOX

Bills at Raiders Odds

  • Odds: Bills -2.5 [Bet Now]
  • Total: 49.5 [Bet Now]
  • Time: 4:25 p.m. ET on Sept. 20
  • TV Channel: CBS

Patriots at Chiefs Odds

  • Odds: Chiefs -7 [Bet Now]
  • Total: N/A
  • Time: 4:25 p.m. ET on Sept. 20
  • TV Channel: CBS

Eagles at 49ers Odds

  • Odds: 49ers -6 [Bet Now]
  • Total: 43 [Bet Now]
  • Time: 8:20 p.m. ET on Sept. 20
  • TV Channel: NBC

Falcons at Packers Odds

  • Odds: N/A
  • Total: N/A
  • Time: 8:15 p.m. ET on Sept. 21
  • TV Channel: ESPN

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