The Seattle Seahawks (11-3) host the rival Los Angeles Rams (11-3) on Thursday Night Football on December 18. Kickoff from Lumen Field in Seattle, Was., is set for 8:15 p.m. ET. TNF will broadcast on Prime Video.
The Seahawks are 1.5-point favorites over the Rams on the spread (Seahawks -1.5), with the over/under set at 43 total points. Seattle is a -125 favorite to win outright on the moneyline; Los Angeles is +105 to pull off the upset.
Below, you can find our Rams vs Seahawks picks for Thursday Night Football, which include predictions for the spread, game total and four player props.
Rams vs Seahawks Picks & Predictions
| Game | Time (ET) | Best Bet |
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  | 8:15 p.m. | |
| 8:15 p.m. | |
| 8:15 p.m. | |
| 8:15 p.m. | |
| 8:15 p.m. | |
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Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | ||
Thursday Night Football Odds
- Rams vs Seahawks Moneyline: Rams +105, Seahawks -125
- Rams vs Seahawks Spread: Rams +1.5, Seahawks -1.5
- Rams vs Seahawks Total: 43
Rams vs Seahawks odds via bet365
Rams vs Seahawks Spread Prediction
By Billy Ward
The line for Thursday Night Football has flipped, with the Rams opening as 1.5-point favorites but the Seahawks now favored by the same margin. While I’m kicking myself for not getting on the line earlier, that move feels entirely justified.
The first factor is the Rams' key injuries, or in this case, one injury in particular. They’ll almost certainly be without No. 2 wide receiver Davante Adams, who reinjured a hamstring last week against the Lions.
Speaking of those Lions, teams have typically struggled the week after facing them in the Dan Campbell era, going 5-8 this season and 5-9 last season (not counting bye weeks) straight up in the following week. That trend is likely due to the physical play of Detroit, which wears on opponents. That factor is probably multiplied by the short week for the Rams, who played the Lions just four days ago.
In addition, the rainy and windy conditions in Seattle tonight also favors the home team. The Rams play indoors and have one of the highest pass rates over expectation (PROE) in the NFL, while Seattle has the lowest PROE and is more accustomed to playing in rough conditions.
With all of those considerations, I’m more than happy to lay the points on Seattle even after the line movement.
Pick: Seahawks -1.5 (-105)
Rams vs Seahawks Over/Under Pick
The reports of windy conditions in Seattle has moved this total down a point below the key number of 44, but I am still willing to play the under in this NFC West divisional game tonight. The Rams and Seahawks have two of the top-five defenses on a points per drive basis and both are excellent against the run.
The foundation of both offensive attacks is the running game, but neither projects for much success in this spot.
Matthew Stafford may be the leading candidate for NFL MVP at this point, but he will have to navigate this game without a healthy Davante Adams. Seattle’s defense has allowed a 27% conversion rate on third down over its last six games, which is the best mark in the NFL. The Seahawks can afford to pay extra attention to Puka Nacua in those key situations and it will be difficult for the Rams to sustain drives.
Los Angeles' defense made life difficult for Sam Darnold in the first meeting, with Darnold throwing four interceptions. I expect Seattle to see light boxes often on early downs and stick to the run even if it isn’t proving to be effective.
This will only shorten the game and it will ultimately translate to a defensive battle that sees the winner scoring 21-24 points at most.
Pick: Under 43; bet to bet to 42.5
Rams vs Seahawks Player Props: Matthew Stafford
I have no idea why this line for Matthew Stafford is so low, but I'm not going to argue.
Yes, Davante Adams' status is in question due to a hamstring injury — and the matchup against the Seahawks is tough — but Stafford has been playing far too well to have a line this low.
Stafford has hit the over at this number in six of the last seven games, and even if Adams doesn't play, Stafford should still be slinging it a decent amount.
Seattle has played zone at a high rate, and Stafford has been a top-2 QB vs. zone this season. He only had 130 yards against the Seahawks the last time these teams played, but the Rams got out to an early lead and Sam Darnold threw four picks that took the pressure off Stafford.
I have Stafford projected for 25 yards over this number, making this a great bet.
Pick: Matthew Stafford Over 228.5 Passing Yards (-114)
Rams vs Seahawks Player Props: Colby Parkinson
Colby Parkinson was stuck in the Rams' 4-man tight end rotation through Week 11. He had an uninspiring 6.1% target share and 23.5% route rate. Parkinson also missed a few games in that stretch.
Since Tyler Higbee went down in Week 11, Parkinson has emerged as the Rams’ clear No. 3 receiving option. He’s posted a 15.2% target share and 55.8% route rate. He’s caught 16-of-20 targets over four games.
The Seahawks have been tremendous on defense, but tight ends have been a weakness. The Seahawks have ceded the second-most receptions, fifth-most targets, and fourth-most yards to the position.
Davante Adams is dealing with a hamstring injury and considered week-to-week, per reports. With a quick turnaround, Adams seems unlikely to play this week. His absence would potentially open up more work for the Rams' remaining pass-catchers.
Pick: Colby Parkinson Over 3.5 Receptions (-105)
Rams vs Seahawks Player Props: Jaxon Smith-Njigba
By Kyle Murray
This number just feels too low for Jaxon Smith-Njigba, who has been one of the most dominant producers in the NFL this season.
JSN has recorded 7+ catches in 10-of-14 (71%) of games this season, and he now gets a matchup against the Rams, who have allowed the third-most targets and receptions per game to wide receivers
In the last matchup between these teams, JSN had nine receptions on 12 targets for 105 yards.
Pick: Jaxon Smith-Njigba Over 6.5 Receptions (-108)
Rams vs Seahawks Anytime Touchdown Pick
By Grant Neiffer
Colby Parkinson has been on a tear recently, and these odds on him to score are far too high.
Parkinson has scored six TDs in his last six games, and he has scored in all but one of those contests. He's been a huge part of this passing game, and with Davante Adams likely not playing, Parkinson should take up some of Adams' TD equity.
The matchup against the Seahawks is tough, but they have funneled targets to TEs (allowing the third-most yards and fifth-most targets to the position).
I have the true odds here around +200.
Pick: Colby Parkinson Anytime Touchdown Scorer (+240)
