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Sabres vs. Penguins Odds & Betting Predictions - September 21, 2026

Sabres at Penguins

11:00 pm • SportsNet PT+

Buffalo Sabres

4-4-2
1
1 - 4

Pittsburgh Penguins

3-6-1
4

Sabres at Penguins Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Sabres
4-4-2
-1.5
+1.5-182
o5.5-129
+142
Penguins
3-6-1
u5.5
-1.5+151
u5.5+107
-170
location pinMonday 11:00 p.m.
September 21, 2026
PPG Paints ArenaPittsburgh

Prop Odds Comparison

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Line Movement Tracker

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Sabres vs. Penguins Public Betting Percentages

Away Logo

Sabres

Public

Home Logo

Penguins

16%

Bets%

84%

Money%

NHL Public Betting Right Arrow

Betting Trends

  • Penguins are 2-3 in their last 5 games.
  • Penguins are 4-1 in their last 5 games against the spread
  • Penguins are 3-4 in their road games against the spread
  • The totals have gone OVER in 2 of Penguins' last 5 games
  • The totals have gone OVER in 1 of Penguins' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Penguins		5-52-13-40-25-3
Sabres		5-52-43-11-34-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Penguins		7-31-26-11-16-2
Sabres		6-42-44-03-13-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Penguins		3-6N/AN/A0-23-5
Sabres		4-4N/AN/A2-22-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 29th@PHIL 0-1+1.5 WU 5.5PHI -101
Apr 27thPHIW 3-2-1.5 LU 5.5PIT -127
Apr 26th@PHIW 4-2+1.5 WO 5.5PIT +105
Apr 22nd@PHIL 2-5-O 5.5PHI -109
Apr 20thPHIL 0-3-1.5 LU 6.5PHI -154

Sabres vs. Penguins Injury Updates

Sabres Injuries

  • Sam Carrick
    C

    Carrick is out with upper body

    Out

  • Matt Grzelcyk
    D

    Grzelcyk is out with lower body

    Out

  • Alex Lyon
    G

    Lyon is out with upper body

    Out

  • Conor Timmins
    D

    Timmins is out with lower body

    Out

  • Justin Danforth
    RW

    Danforth is out with upper body

    Out

Penguins Injuries

  • Trevor van Riemsdyk
    D

    van Riemsdyk is day-to-day with lower body

    Day-to-Day

  • Bryan Rust
    RW

    Rust is out with lower body

    Out

  • Samuel Girard
    D

    Girard is day-to-day with undisclosed

    Day-to-Day

  • Justin Brazeau
    RW

    Brazeau is out with lower body

    Out

  • Ryan Graves
    D

    Graves is out with lower body

    Out

  • Benjamin Kindel
    C

    Kindel is out with undisclosed

    Out

See more NHL Injuries Right Arrow
Team Stats

1
Goals
4
2
Assists
6
2
Penalties
3
24
Shots
28
14
Hits
20
24
Faceoffs Won
28

Sabres vs. Penguins Odds Comparison

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Sabres at Penguins Team Totals

MatchupOverUnder
Sabres
4-4-2
N/A
N/A
Penguins
3-6-1
N/A
N/A