Cubs vs. Pirates Odds & Betting Predictions - May 25, 2026

Cubs at Pirates

5:35 pm • SportsNet PT
1 - 2
Starting Pitchers
pitcherteameraw-l
Carmen Mlodzinski logoC.MlodzinskiPittsburgh Pirates logo3.764-3
Ben Brown logoB.BrownChicago Cubs logo2.021-2

Cubs at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
29-25
-1.5
-1.5+134
o8.5-109
-124
Pirates
28-26
u8
+1.5-162
u8.5-110
+105
location pinMonday 5:35 p.m.
May 25, 2026
PNC ParkPittsburgh
Cubs vs. Pirates Expert Picks
Wags Wins
Wags Wins
Last 30d: 217-290-5 (-95.6u)
CHC -125
2u
OldSchool0909
Last 30d: 56-57-0 (+9.1u)
PIT +113
1.13u
Ryan Minion
Ryan Minion
Last 30d: 339-370-16 (+0.2u)
P.Crow-Armstrong o1.5 Total Bases+120
$1.00
CHC -125
$1.25
Frank Ammirante
Frank Ammirante
Last 30d: 232-255-10 (-12.8u)
B.Brown o5.5 Ks+121
1u
Adam Kaufman
Adam Kaufman
Last 30d: 46-50-0 (-8.3u)
PIT -104
1u
Sean Zerillo
Sean Zerillo
Last 30d: 175-144-11 (+6.6u)
CHC -110
0.55u
Bet to -120

Cubs vs. Pirates Previews & Analysis

  • The Leadoff: Anderson's MLB Breakdown & Bets for Monday article feature image

    The Leadoff: Anderson's MLB Breakdown & Bets for Monday

    Jon Anderson
    May 25, 2026 UTC
  • Zerillo's Projection for Cubs-Pirates article feature image

    Zerillo's Projection for Cubs-Pirates

    Tanner McGrath
    May 25, 2026 UTC
  • +300, +470, +520 Data Model HR Picks article feature image

    +300, +470, +520 Data Model HR Picks

    Alex Kolodziej
    May 25, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Pirates Public Betting Percentages

Away Logo

Cubs

Public

58%

Bets%

42%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates
29-2514-1315-1216-1312-12
Cubs
21-3312-179-1614-227-11

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates
27-25-216-1111-14-217-129-13-2
Cubs
29-2515-1414-1118-1811-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates
28-2614-1314-1317-1210-14
Cubs
29-2518-1111-1421-158-10

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 24th@TORW 4-1+1.5 WU 7.5PIT +145
May 23rd@TORL 2-5-1.5 LU 7.5TOR -144
May 22nd@TORL 2-6+1.5 LU 8TOR +137
May 21st@STLW 6-2-1.5 WO 7PIT -121
May 20th@STLW 7-0-1.5 WU 7.5PIT -103

Pirates vs. Cubs Injury Updates

Pirates Injuries

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

Cubs vs. Pirates Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Ben Brown logoRB.Brown, P83671
Trent Thornton logoRT.Thornton, P21101
Jacob Webb logoRJ.Webb, P23120
HITTERSH-ABRHRRBI
Pete Crow-Armstrong logo1P.Crow-Armstrong, CF0-4000
Ian Happ logo2I.Happ, LF0-3000
Michael Busch logo3M.Busch, 1B1-4111
Alex Bregman logo4A.Bregman, 3B2-4000
Michael Conforto logo5M.Conforto, RF0-4000
Pedro Ramirez logo6P.Ramirez, 2B1-3000
Nico Hoerner logo6N.Hoerner, PH0-1000
Moises Ballesteros logo7M.Ballesteros, DH2-2000
Seiya Suzuki logo7S.Suzuki, PH0-1000
Miguel Amaya logo8M.Amaya, C0-2000
Carson Kelly logo8C.Kelly, PH0-1000
Dansby Swanson logo9D.Swanson, SS0-3000
Pirates Player Stats
Projected
PITCHERPCIPKER
Carmen Mlodzinski logoRC.Mlodzinski, P86521
Wilber Dotel logoRW.Dotel, P41340
Gregory Soto logoLG.Soto, P14110
HITTERSH-ABRHRRBI
Spencer Horwitz logo1S.Horwitz, 1B2-3100
Brandon Lowe logo2B.Lowe, 2B2-4001
Bryan Reynolds logo3B.Reynolds, RF1-4000
Nick Gonzales logo4N.Gonzales, 3B0-4000
Oneil Cruz logo5O.Cruz, CF2-4000
Marcell Ozuna logo6M.Ozuna, DH0-4000
Konnor Griffin logo7K.Griffin, SS0-3000
Jhostynxon Garcia logo8J.Garcia, LF0-3000
Henry Davis logo9H.Davis, C1-3111

Cubs vs. Pirates Odds Comparison

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Cubs at Pirates Team Totals

MatchupOverUnder
Cubs
29-25
N/A
N/A
Pirates
28-26
N/A
N/A