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Cubs vs. Guardians Odds & Betting Predictions - April 5, 2026

Cubs at Guardians

8:40 pm • MARQ

Chicago Cubs

3-4
@

Cleveland Guardians

5-3
Starting Pitchers
pitcherteameraw-l
Parker Messick logoP.MessickCleveland Guardians logo0.001-0
Shota Imanaga logoS.ImanagaChicago Cubs logo7.200-1

Cubs at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
3-4
-1.5
-1.5+130
o7.5+102
-130
Guardians
5-3
u7
+1.5-155
u7.5-120
+110
location pinSunday 8:40 p.m.
April 05, 2026
Progressive FieldCleveland
thermometer image42°Fahrenheit
rain image0%Rain
wind image17Wind
Cubs vs. Guardians Expert Picks
Doug Ziefel
Doug Ziefel
Last 30d: 218-283-16 (-12.1u)
CHC -123
0.62u
OldSchool0909
Last 30d: 104-112-1 (-11.6u)
CLE +108
1u

Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Guardians Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Guardians

66%

Bets%

34%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 3-2 in their last 5 games.
  • Guardians are 3-2 in their last 5 games against the spread
  • Guardians are 4-3 in their road games against the spread
  • The totals have gone OVER in 1 of Guardians' last 5 games
  • The totals have gone OVER in 0 of Guardians' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		5-31-04-31-04-3
Cubs		3-43-30-13-30-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		3-50-13-40-13-4
Cubs		3-43-30-13-30-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		5-31-04-31-04-3
Cubs		3-43-30-13-30-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 3rdCHCW 4-1-U 7.5CLE -115
Apr 2nd@LADW 4-1+1.5 WU 8CLE +245
Apr 1st@LADL 1-4---
Mar 31st@LADW 4-2+1.5 WU 8.5CLE +158
Mar 29th@SEAL 0-8+1.5 LO 7.5SEA +122

Guardians vs. Cubs Injury Updates

Guardians Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    • Jordan Wicks
      SP

      Wicks is out with arm

      Out

    • Seiya Suzuki
      RF

      Suzuki is out with knee

      Out

    See more MLB Injuries Right Arrow
    Cubs vs. Guardians Starting Lineups
    Cubs Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Shota Imanaga logoLS.Imanaga, P0-17.201.60012.60
    HITTERSAVGOBPSLGHR
    Nico Hoerner logo1N.Hoerner, 2B.292.400.4580
    Alex Bregman logo2A.Bregman, 3B.214.313.4292
    Ian Happ logo3I.Happ, LF.179.281.5363
    Carson Kelly logo4C.Kelly, C.250.348.2500
    Michael Busch logo5M.Busch, 1B.240.367.3200
    Dansby Swanson logo6D.Swanson, SS.143.296.1430
    Matt Shaw logo7M.Shaw, RF.222.211.2220
    Pete Crow-Armstrong logo8P.Crow-Armstrong, CF.269.321.3080
    Miguel Amaya logo9M.Amaya, DH.400.455.8001
    Guardians Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Parker Messick logoLP.Messick, P1-00.000.8337.50
    HITTERSAVGOBPSLGHR
    Steven Kwan logo1S.Kwan, CF.233.324.2670
    Angel Martinez logo2A.Martinez, LF.167.318.2220
    Jose Ramirez logo3J.Ramirez, 3B.188.235.3441
    David Fry logo4D.Fry, DH.286.286.4290
    Chase DeLauter logo5C.DeLauter, RF.346.370.9235
    Rhys Hoskins logo6R.Hoskins, 1B.286.444.4290
    Gabriel Arias logo7G.Arias, SS.143.217.4292
    Austin Hedges logo8A.Hedges, C.500.500.7500
    Brayan Rocchio logo9B.Rocchio, 2B.227.370.2730

    Cubs vs. Guardians Odds Comparison

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    Cubs at Guardians Team Totals

    MatchupOverUnder
    Cubs
    3-4
    N/A
    N/A
    Guardians
    5-3
    N/A
    N/A