Astros vs. Athletics Odds & Betting Predictions - September 25, 2025

Astros at Athletics

2:05 am • SCHN

Houston Astros

84-74

0 - 6

Athletics

75-83

pitcher		team	era	w-l
L.Severino			4.54	8-11
H.Brown			2.43	12-9

MatchupOpenSpreadTotalMoneyline
Astros 84-74	-1.5	-1.5+122	o9-110	-135
Athletics 75-83	u9	+1.5-145	u9-105	+112

Thursday 2:05 a.m.

September 25, 2025

Sutter Health ParkWest Sacramento

HOU -0.5 (F5)+105

ATH +111

3.33u

📚Player Profit 🔑 A’s ML +111 (Player Profit) 3u This line screams A’s to me. Public all over the Astros, Hunter Brown on the bump but the line says this is gonna be very close. Give me the value. Astros are free falling, A’s mash, love this spot. Sharp money on them too Code: sirlocks for 10% off every deposit at https://www.playerprofit.com/

HOU -1.5+128

HOU -132

L.Butler u0.5 Runs Scored-139

ATH +125

0.63u

Bet to +115

L.Butler u0.5 Runs Scored-139

0.72u

Today's MLB Best Bets
Action Network Staff•
Sep 24, 2025 UTC

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No props found

MLB Public Betting

Athletics are 3-2 in their last 5 games.
Athletics are 2-3 in their last 5 games against the spread
Athletics are 47-34 in their road games against the spread
The totals have gone OVER in 1 of Athletics' last 5 games
The totals have gone OVER in 38 of Athletics' 77 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Athletics	85-73	38-39	47-34	14-23	69-48
Astros	79-79	37-44	42-35	40-59	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Athletics	75-75-8	38-37-2	37-38-6	14-21-2	59-52-6
Astros	71-80-7	36-43-2	35-37-5	44-53-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Athletics	75-83	35-42	40-41	17-20	55-62
Astros	84-74	46-35	38-39	53-46	31-26

date	opponent	score	spread	over/under	moneyline
Sep 24th	HOU	W 5-1	+1.5 W	U 10	ATH -116
Sep 21st	@PIT	L 0-11	-1.5 L	O 8.5	PIT +100
Sep 20th	@PIT	L 0-2	-1.5 L	U 8	PIT -113
Sep 19th	@PIT	W 4-3	-1.5 L	U 8.5	ATH -112
Sep 18th	@BOS	W 5-3	+1.5 W	U 9	ATH +126

Luis Medina
SP
Medina is out with elbow
Out
Brady Basso
RP
Basso is out with shoulder
Out

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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PITCHER	PC	IP	K	ER
RH.Brown, P	86	5	5	4
LS.Okert, P	12	1	1	0
LB.King, P	13	1	0	2
RN.Hernandez, P	16	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Altuve, 2B	1-3	0	0	0
2I.Paredes, DH	1-4	0	0	0
3C.Correa, SS	2-4	0	0	0
4C.Walker, 1B	1-4	0	0	0
5J.Sanchez, LF	0-2	0	0	0
5C.Smith, PH	0-1	0	0	0
5C.Smith, RF	0-1	0	0	0
5V.Caratini, PH	0-1	0	0	0
6Y.Diaz, C	0-3	0	0	0
7J.Meyers, CF	0-3	0	0	0
8Z.Cole, RF	0-2	0	0	0
8Z.Cole, LF	0-2	0	0	0
8M.Dubon, PH	0-1	0	0	0
8M.Dubon, LF	0-1	0	0	0
9R.Urias, 3B	0-3	0	0	0

PITCHER	PC	IP	K
RL.Severino, P	85	6.1	5
LH.Harris, P	19	1.2	2
RE.Alvarado, P	32	1	2

HITTERS	H-AB	R	HR	RBI
1N.Kurtz, 1B	0-2	2	0	0
2S.Langeliers, C	4-4	2	1	2
3T.Soderstrom, LF	2-4	1	1	2
4B.Rooker, DH	1-4	0	0	2
5J.Wilson, SS	0-4	0	0	0
6L.Butler, CF	0-4	0	0	0
7M.Schuemann, 2B	0-3	0	0	0
8J.Bleday, RF	0-2	0	0	0
8C.Thomas, PH	0-2	0	0	0
8C.Thomas, RF	0-2	0	0	0
9B.Harris, 3B	1-3	1	0	0