Orioles vs. Guardians Odds & Betting Predictions - July 21, 2025
Orioles at Guardians
10:40 pm • MASN2Starting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.25 | 12-11 | ||
![]() | 4.64 | 10-10 |
Orioles at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Orioles 0-0 | +1.5 | +1.5-182 | o8.5-105 | +118 |
Guardians 5-6 | u8 | -1.5+151 | u8.5-115 | -143 |

Progressive FieldCleveland
Orioles vs. Guardians Expert Picks

Sean Zerillo
Last 30d: 134-117-6 (+6.6u)
Over 8-115
0.25u
Small to 8.5 (-105)
Matt DiLeo
Last 30d: 58-42-0 (+10.5u)
T.Sugano o15.5 Outs+100
1u
Ryan Minion
Last 30d: 255-269-8 (-1.9u)
A.Martinez o1.5 Hits + Runs + RBIs+110
$1.10
OldSchool0909
Last 30d: 53-37-0 (+16.5u)
CLE -135
0.74u
CLE -1.5+160
1.6u
The Degenerates
Last 30d: 73-67-1 (-0.3u)
CLE -137
1u
Allan Lem
Last 30d: 52-40-0 (+1.0u)
Under 8.5-114
0.57u
Have a slight lean on the under here as I’m projecting this closer to 8.2. Backing Sugano is scary given he’s a pitch-to-contact player but he limits walks and this Guardians offense is potentially a bottom-5 offense.
Trusting Bibee to slow down the Orioles as he has a 4.29 ERA but a 3.64 xERA under it.
Let’s roll the dice here.
Topper
Last 30d: 106-88-4 (+4.4u)
Under 4.5 (F5)-115
1.15u
Wind-In First 5 Unders (***)
Overall: 312-200-32,61% (ROI:17%)
Season:24-6-0,80% (ROI:52%)
Under 8.5-115
1.15u
Wind Wins Unders (***)
Overall: 1071-732-81,59% (ROI:14%)
Season:40-34-3,54% (ROI:3%)
Al’s Analytics
Last 30d: 0-0-0 (+0.0u)
Over 8-120
0.83u
Game 1 Overs ( O/U 8-8.5 )
95-48-3 (66.43%) 26.28% ROI
2 Straight Overs + Underdog Previous Game
51-23 (68.92%) 31.57% ROI
Dan Bellino Ump Trends
7-1 to the over with the line between 8-8.5 in 2025
75-34 to the over when the home team is favored
Prop Odds Comparison
Line Movement Tracker
Orioles vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 4-1 in their last 5 games against the spread
- Guardians are 43-38 in their road games against the spread
- The totals have gone OVER in 2 of Guardians' last 5 games
- The totals have gone OVER in 42 of Guardians' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Orioles vs. Guardians Injury Updates

Orioles Injuries
- Jordan Westburg3B
Westburg is out with elbow
Out

Guardians Injuries
Orioles vs. Guardians Box Score
Orioles Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 90 | 3.2 | 4 | 3 | |
![]() | 22 | 1 | 1 | 1 | |
![]() | 22 | 1.1 | 0 | 1 | |
![]() | 39 | 2 | 2 | 4 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 1 |
![]() | 0-4 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 4 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 86 | 7 | 4 | 3 | |
![]() | 14 | 1 | 2 | 0 | |
![]() | 12 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-3 | 1 | 0 | 0 |
![]() | 2-5 | 2 | 0 | 0 |
![]() | 1-5 | 3 | 1 | 3 |
![]() | 2-3 | 1 | 1 | 1 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 2-5 | 0 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 1 |
![]() | 2-4 | 0 | 0 | 2 |
![]() | 2-5 | 1 | 1 | 1 |
Orioles vs. Guardians Odds Comparison
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Orioles at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Orioles 0-0 | N/A | N/A |
Guardians 5-6 | N/A | N/A |


























