Orioles vs. Red Sox Odds & Betting Predictions - July 22, 2026

Orioles at Red Sox

5:35 pm • NESN
3 - 6
Starting Pitchers
pitcherteameraw-l
Jake Bennett logoJ.BennettBoston Red Sox logo3.699-7
Dean Kremer logoD.KremerBaltimore Orioles logo6.501-4

Orioles at Red Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
71-76
+1.5
+1.5-152
o9.5-105
+144
Red Sox
80-67
u9.5
-1.5+118
u9.5-115
-175
location pinWednesday 5:35 p.m.
July 22, 2026
Fenway ParkBoston
Orioles vs. Red Sox Expert Picks
Austin Pendergrass
Austin Pendergrass
Last 30d: 33-28-0 (+2.4u)
BOS -144
0.35u
Matthew Lopes
Matthew Lopes
Last 30d: 52-211-1 (+23.8u)
W.Abreu To Hit 1+ Home Runs Yes+335
1u
W.Contreras To Hit 1+ Home Runs Yes+300
1u
Frank Ammirante
Frank Ammirante
Last 30d: 268-316-7 (-38.6u)
J.Bennett u1.5 BB-125
1u
Under 9.5-110
1u
Zense
Zense
Last 30d: 4-5-0 (-2.0u)
BOS -140
0.71u
Sandy Plashkes
Sandy Plashkes
Last 30d: 48-56-0 (-2.2u)
BAL +142
1u
Wags Wins
Wags Wins
Last 30d: 224-170-3 (+41.8u)
BOS -1.5+145
1.45u
Adam Kaufman
Adam Kaufman
Last 30d: 85-97-0 (-26.7u)
BOS -140
1u
OldSchool0909
Last 30d: 84-97-1 (-11.0u)
BAL +120
1u

Orioles vs. Red Sox Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. Red Sox Public Betting Percentages

Away Logo

Orioles

Public

16%

Bets%

84%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Red Sox
70-7731-4139-3646-5823-19
Orioles
74-7338-3736-3631-3842-34

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Red Sox
69-74-434-35-335-39-150-51-319-22-1
Orioles
73-70-434-38-339-32-132-35-240-34-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Red Sox
80-6736-3644-3157-4722-20
Orioles
71-7636-3935-3737-3233-43

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jul 20thBALW 6-5-1.5 LO 8.5BOS -166
Jul 19thTBW 6-1-1.5 WU 8.5BOS -125
Jul 18thTBW 7-6+1.5 WO 9.5BOS -119
Jul 17thTBW 5-3-1.5 WU 9BOS -131
Jul 17thTBW 10-0+1.5 WO 8.5BOS -118

Orioles vs. Red Sox Injury Updates

Orioles Injuries

  • Jordan Westburg
    3B

    Westburg is out with elbow

    Out

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Triston Casas
    1B

    Casas is out with knee

    Out

  • Kutter Crawford
    SP

    Crawford is out with wrist

    Out

Orioles vs. Red Sox Box Score
Orioles Player Stats
Projected
PITCHERPCIPKER
Dean Kremer logoRD.Kremer, P87656
Anthony Nunez logoRA.Nunez, P27210
HITTERSH-ABRHRRBI
Taylor Ward logo1T.Ward, LF1-4000
Pete Alonso logo2P.Alonso, 1B2-5100
Gunnar Henderson logo3G.Henderson, SS1-4000
Tyler O'Neill logo4T.O'Neill, RF1-4001
Coby Mayo logo5C.Mayo, DH1-3100
Colton Cowser logo5C.Cowser, PH0-1000
Colton Cowser logo5C.Cowser, DH0-1000
Leody Taveras logo6L.Taveras, CF0-4000
Christian Encarnacion-Strand logo7C.Encarnacion-Strand, 3B3-4112
Jackson Holliday logo8J.Holliday, 2B2-4000
Sam Huff logo9S.Huff, C0-2000
Johnathan Rodriguez logo9J.Rodriguez, PH0-0000
Dylan Beavers logo9D.Beavers, PH0-1000
Chadwick Tromp logo9C.Tromp, C0-1000
Red Sox Player Stats
Projected
PITCHERPCIPKER
Jake Bennett logoLJ.Bennett, P835.243
Justin Slaten logoRJ.Slaten, P191.110
Garrett Whitlock logoRG.Whitlock, P12100
Aroldis Chapman logoLA.Chapman, P13100
HITTERSH-ABRHRRBI
Masataka Yoshida logo1M.Yoshida, DH1-3100
Ceddanne Rafaela logo2C.Rafaela, CF2-4211
Wilyer Abreu logo3W.Abreu, RF0-4000
Willson Contreras logo4W.Contreras, 1B2-4100
Caleb Durbin logo5C.Durbin, 3B2-4202
Romy Gonzalez logo6R.Gonzalez, 2B1-4000
Jarren Duran logo7J.Duran, LF1-3003
Connor Wong logo8C.Wong, C0-3000
Tsung-Che Cheng logo9T.Cheng, SS0-3000

Orioles vs. Red Sox Odds Comparison

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Orioles at Red Sox Team Totals

MatchupOverUnder
Orioles
71-76
N/A
N/A
Red Sox
80-67
N/A
N/A