Pirates vs. Reds Odds & Betting Predictions - September 23, 2025

Pirates at Reds

10:40 pm • SportsNet PT
@
Starting Pitchers
pitcherteameraw-l
Brady Singer logoB.SingerCincinnati Reds logo3.8614-10
Johan Oviedo logoJ.OviedoPittsburgh Pirates logo3.522-0

Pirates at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pirates
67-89
+1.5
+1.5-160
o8.5-110
+134
Reds
80-76
u8.5
-1.5+132
u8.5-110
-160
location pinTuesday 10:40 p.m.
September 23, 2025
Great American Ball ParkCincinnati
thermometer image75°Fahrenheit
rain image0%Rain
wind image2Wind
Pirates vs. Reds Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 158-168-4 (-3.5u)
Over 8.5+100
0.5u
Exchange. Bet to -120
Allan Lem
Allan Lem
Last 30d: 113-103-6 (-0.1u)
CIN -150
0.75u
Don’t love the odds we’re getting but I’m buying the Reds here. I’m actually a Johan Oviedo fan but his 12.9% BB% is just not cutting it right now. Reds are surging and playing for a wild card spot, so they are going to treat this like a playoff game and throw everything they’ve got at them Pirates. Brady Singer limits walks and home runs, and now faces a Pirates offense that averages the fewest runs per game (3.60).

Prop Odds Comparison

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Line Movement Tracker

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Pirates vs. Reds Public Betting Percentages

Away Logo

Pirates

Public

19%

Bets%

81%

Money%

MLB Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds
80-7440-3640-3829-4051-33
Pirates
85-7148-3337-3819-2664-44

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds
57-87-1026-43-731-44-320-45-436-42-6
Pirates
60-88-833-43-527-45-317-26-241-61-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds
80-7643-3336-4238-3141-43
Pirates
67-8944-3723-5222-2344-64

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 21stCHCW 1-0-1.5 LU 9CIN -126
Sep 20thCHCW 6-3+1.5 WU 9CIN -114
Sep 19thCHCW 7-4+1.5 WO 8CIN -110
Sep 18thCHCW 1-0-1.5 LU 8.5CIN -145
Sep 17th@STLW 6-2-1.5 WU 8.5CIN -120

Pirates vs. Reds Injury Updates

Pirates Injuries

  • Johan Oviedo
    SP

    Oviedo is questionable with elbow

    Questionable

  • Endy Rodriguez
    1B

    Rodriguez is out with elbow

    Out

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Reds Injuries

  • Noelvi Marte
    3B

    Marte is day-to-day with side

    Day-to-Day

  • Reiver Sanmartin
    RP

    Sanmartin is out with elbow

    Out

  • Brandon Williamson
    SP

    Williamson is out for season with elbow

    Out for Season

  • Graham Ashcraft
    RP

    Ashcraft is out with groin

    Out

  • Chase Burns
    SP

    Burns is out with hip

    Out

  • Julian Aguiar
    SP

    Aguiar is out for season with elbow

    Out for Season

  • Rhett Lowder
    SP

    Lowder is out with elbow

    Out

  • Carson Spiers
    RP

    Spiers is out with shoulder

    Out

Pirates vs. Reds Starting Lineups
Pirates Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Johan Oviedo logoRJ.Oviedo, P2-03.521.2399.39
HITTERSAVGOBPSLGHR
Oneil Cruz logo1O.Cruz, CF.203.303.37919
Jared Triolo logo2J.Triolo, 3B.233.321.3677
Bryan Reynolds logo3B.Reynolds, RF.244.316.40316
Spencer Horwitz logo4S.Horwitz, 1B.257.338.4029
Andrew McCutchen logo5A.McCutchen, DH.240.336.37213
Nick Gonzales logo6N.Gonzales, SS.267.306.3715
Jack Suwinski logo7J.Suwinski, LF.131.274.2343
Nick Yorke logo8N.Yorke, 2B.220.250.3401
Henry Davis logo9H.Davis, C.163.233.2676
Reds Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Brady Singer logoRB.Singer, P14-103.861.2248.67
HITTERSAVGOBPSLGHR
TJ Friedl logo1T.Friedl, CF.257.360.37113
Gavin Lux logo2G.Lux, DH.267.351.3725
Noelvi Marte logo3N.Marte, RF.272.312.46513
Spencer Steer logo4S.Steer, 1B.241.311.41921
Will Benson logo5W.Benson, LF.228.274.44712
Elly De La Cruz logo6E.De La Cruz, SS.263.336.43620
Tyler Stephenson logo7T.Stephenson, C.224.310.40912
Ke'Bryan Hayes logo8K.Hayes, 3B.238.317.3573
Matt McLain logo9M.McLain, 2B.224.304.35215

Pirates vs. Reds Odds Comparison

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Pirates at Reds Team Totals

MatchupOverUnder
Pirates
67-89
N/A
N/A
Reds
80-76
N/A
N/A