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Cubs vs. Reds Odds & Betting Predictions - September 19, 2025

Cubs at Reds

10:40 pm • MARQ
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Chicago Cubs

87-64
@

Cincinnati Reds

75-76
Starting Pitchers
pitcherteameraw-l
Nick Lodolo logoN.LodoloCincinnati Reds logo0.000-0
Shota Imanaga logoS.ImanagaChicago Cubs logo0.000-0

Cubs at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
87-64
N/A
N/A
N/A
Reds
75-76
N/A
N/A
N/A
location pinFriday 10:40 p.m.
September 19, 2025
Great American Ball ParkCincinnati
thermometer image82°Fahrenheit
rain image0%Rain
wind image2Wind

Prop Odds Comparison

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No props found

Line Movement Tracker

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Cubs vs. Reds Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Reds

50%

Bets%

50%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Reds are 1-4 in their last 5 games.
  • Reds are 1-4 in their last 5 games against the spread
  • Reds are 39-38 in their road games against the spread
  • The totals have gone OVER in 3 of Reds' last 5 games
  • The totals have gone OVER in 25 of Reds' 72 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds		77-7238-3439-3827-3850-33
Cubs		71-8035-4036-4050-5820-22

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds		56-84-925-41-631-43-320-42-335-42-6
Cubs		67-75-935-35-532-40-446-55-721-19-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds		75-7639-3335-4234-3140-43
Cubs		87-6446-2941-3568-4018-24

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 17th@STLW 6-2-1.5 WU 8.5CIN -120
Sep 16th@STLL 0-3-1.5 LU 8STL -123
Sep 15th@STLW 11-6-1.5 WO 8.5CIN -104
Sep 14th@ATHL 4-7-1.5 LO 9.5ATH -112
Sep 14th@ATHL 5-11-1.5 LO 9ATH -121

Cubs vs. Reds Injury Updates

Cubs Injuries

  • Michael Soroka
    SP

    Soroka is out with shoulder

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

Reds Injuries

  • Noelvi Marte
    3B

    Marte is day-to-day with side

    Day-to-Day

  • Reiver Sanmartin
    RP

    Sanmartin is out with elbow

    Out

  • Brandon Williamson
    SP

    Williamson is out for season with elbow

    Out for Season

  • Graham Ashcraft
    RP

    Ashcraft is out with groin

    Out

  • Chase Burns
    SP

    Burns is out with hip

    Out

  • Julian Aguiar
    SP

    Aguiar is out for season with elbow

    Out for Season

  • Rhett Lowder
    SP

    Lowder is out with elbow

    Out

  • Carson Spiers
    RP

    Spiers is out with shoulder

    Out

See more MLB Injuries Right Arrow

Cubs vs. Reds Odds Comparison

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Cubs at Reds Team Totals

MatchupOverUnder
Cubs
87-64
N/A
N/A
Reds
75-76
N/A
N/A