The Cincinnati Reds host the Pittsburgh Pirates on September 23, 2025. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT; the game will be broadcast on SportsNet PT.
Find my MLB betting preview and Pirates vs Reds prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Pirates vs Reds Prediction
- Pirates vs Reds picks: Over 8.5 (-110, bet365)
My Pirates vs Reds best bet is on Over 8.5. Make sure to find the best odds by checking our live MLB odds page.
Pirates vs Reds Odds
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +129 | 8.5 -110o / -110u | +142 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -156 | 8.5 -110o / -110u | -168 |
Pirates vs Reds Projected Starting Pitchers
| RHP Johan Oviedo (PIT) | Stat | RHP Brady Singer (CIN) |
|---|---|---|
| 2-0 | W-L | 28-14 |
| 0.3 | fWAR (FanGraphs) | 2.9 |
| 3.52/4.15 | ERA /xERA | 3.86/4.18 |
| 4.71/4.92 | FIP / xFIP | 3.90/4.22 |
| 1.24 | WHIP | 1.22 |
| 11.4% | K-BB% | 14.2% |
| 31.3% | GB% | 39.5% |
| 102 | Stuff+ | 95 |
| 90 | Location+ | 100 |
Pirates vs Reds Prediction, Betting Analysis
Looking at this game, I like Over 8.5 at even money, even up to -120. I make this about nine and a quarter.
Both of these offenses have been struggling. Over the last 30 days, the Reds are 22nd and the Pirates 28th, but I think this number is too low for the Great American Ball Park.
The weather will be neutral tonight, with a temperature of 77 degrees and winds of only 2-3 mph, so there will be really no impact.
Over the last three years, on a rolling three-year average, this is a plus-6% park for run scoring, which is the fourth-best in MLB. It's actually been neutral this year. I think that is an outlier and some negative variance from 2022 to 2024.
It's played 10% higher than it did last year and 4% higher than it was over the past three years combined. So, that is what this park is. It's actually projects closer to 15% above the major league average.
That's roughly where I have it tonight, about 13% above a league-average park, which gets me closer to 9.3 projected run.
I'm taking over 8.5 to -120, or you could even take over 9 and even money, but I prefer the Over 8.5.
Pick: Over 8.5 (-110, bet365)
Moneyline
I have no bet on the Moneyline
Run Line (Spread)
I'm making no bets on the Spread
Over/Under
I'm taking Over 8.5 in this matchup
Pirates vs Reds Betting Trends
