Yankees vs. Guardians Odds & Betting Predictions - April 21, 2025

Yankees at Guardians

10:10 pm • YES
4 - 6
Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.0612-5
Clarke Schmidt logoC.SchmidtNew York Yankees logo3.324-4

Yankees at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Yankees
3-4
-1.5
-1.5+131
o8.5-122
-130
Guardians
1-2
u8.5
+1.5-155
u8.5+102
+110
location pinMonday 10:10 p.m.
April 21, 2025
Progressive FieldCleveland
Yankees vs. Guardians Expert Picks
The Degenerates
The Degenerates
Last 30d: 83-82-2 (-5.4u)
NYY -120 (Live)
1.2u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 161-164-13 (+9.2u)
K.Manzardo o0.5 HR+525
0.53u
Gilles Gallant
Gilles Gallant
Last 30d: 22-60-0 (-1.4u)
C.Schmidt o4.5 Ks+110
0.55u
#Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 41-30-0 (+5.5u)
C.Schmidt o4.5 Ks+100
1u
Proj closer to -120, but has a Priority Score of +21.7
Boomer Betz
Boomer Betz
Last 30d: 194-181-10 (+25.3u)
CLE +113
2.26u
#BQ
Austin Pendergrass
Austin Pendergrass
Last 30d: 32-46-0 (-13.7u)
NYY -124
1u
Shady Biev
Shady Biev
Last 30d: 0-0-0 (+0.0u)
NYY -128
2.56u
Royals Props
Royals Props
Last 30d: 40-42-2 (-7.4u)
NYY -121
1.21u
PX
💰🦡 Jake
💰🦡 Jake
Last 30d: 87-105-4 (-12.9u)
Over 8.5-115
1u
Steak Friend
Steak Friend
Last 30d: 0-0-0 (+0.0u)
CLE +100
1u
Grant Neiffer
Grant Neiffer
Last 30d: 36-89-10 (-5.4u)
K.Manzardo o0.5 HR+575
2.88u
Greg DiNardo
Greg DiNardo
Last 30d: 0-0-0 (+0.0u)
NYY -120
1.2u
Matt DiLeo
Matt DiLeo
Last 30d: 54-39-5 (+8.0u)
C.Schmidt o14.5 Outs-135
1u
Boomer Betz
Boomer Betz
Last 30d: 194-181-10 (+25.3u)
J.Ramirez o0.5 HR+520
1.04u
Day 2
Capper Central
Capper Central
Last 30d: 82-72-0 (+2.4u)
Over 8-128
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 161-164-13 (+9.2u)
A.Judge o0.5 HR+250
0.4u
5.63% ev
Sean Zerillo
Sean Zerillo
Last 30d: 63-58-1 (+1.6u)
Over 8.5+100
0.5u
Bet to -105

Yankees vs. Guardians Previews & Analysis

  • Koerner's K Prop for Monday Night article feature image

    Koerner's K Prop for Monday Night

    Sean Koerner
    Apr 21, 2025 UTC
  • Yankees vs. Guardians: Back NY in ALCS Rematch article feature image

    Yankees vs. Guardians: Back NY in ALCS Rematch

    Sean Paul
    Apr 21, 2025 UTC
  • +2825 Home Run Parlay for Monday Night article feature image

    +2825 Home Run Parlay for Monday Night

    Grant Neiffer
    Apr 21, 2025 UTC
  • Tonight's 4 MLB Best Bets article feature image

    Tonight's 4 MLB Best Bets

    Action Network Staff
    Apr 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Yankees vs. Guardians Public Betting Percentages

Away Logo

Yankees

Public

82%

Bets%

18%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
86-7639-4247-3433-3651-38
Yankees
78-8443-3835-4668-729-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
69-87-637-41-332-46-334-34-134-50-5
Yankees
76-81-536-44-140-37-464-73-311-8-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
88-7445-3643-3844-2543-46
Yankees
94-6850-3144-3785-558-13

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 20th@PITW 5-4-1.5 LO 8CLE +105
Apr 19th@PITW 3-0+1.5 WU 8CLE +145
Apr 18th@PITW 10-7-1.5 WO 9CLE -130
Apr 17th@BALL 2-6+1.5 LU 8BAL +116
Apr 16th@BALL 1-9+1.5 LO 8BAL +109

Guardians vs. Yankees Injury Updates

Guardians Injuries

    Yankees Injuries

    • Gerrit Cole
      SP

      Cole is out for season with elbow

      Out for Season

    Yankees vs. Guardians Box Score
    Yankees Player Stats
    Projected
    PITCHERPCIPKER
    Clarke Schmidt logoRC.Schmidt, P80475
    Yoendrys Gomez logoRY.Gomez, P46301
    Ryan Yarbrough logoLR.Yarbrough, P13100
    HITTERSH-ABRHRRBI
    Austin Wells logo1A.Wells, C0-5000
    Aaron Judge logo2A.Judge, DH1-4000
    Cody Bellinger logo3C.Bellinger, CF1-4000
    Paul Goldschmidt logo4P.Goldschmidt, 1B2-3100
    Jazz Chisholm logo5J.Chisholm, 2B1-4112
    Anthony Volpe logo6A.Volpe, SS1-3100
    Jasson Dominguez logo7J.Dominguez, LF1-4112
    Pablo Reyes logo8P.Reyes, RF1-3000
    Ben Rice logo8B.Rice, PH0-1000
    Oswaldo Cabrera logo9O.Cabrera, 3B2-4000
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P1046.182
    Paul Sewald logoRP.Sewald, P191.112
    Joey Cantillo logoLJ.Cantillo, P90.110
    Cade Smith logoRC.Smith, P11120
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF2-4200
    Nolan Jones logo2N.Jones, RF0-3000
    Jhonkensy Noel logo2J.Noel, PH0-1000
    Jhonkensy Noel logo2J.Noel, RF0-1000
    Jose Ramirez logo3J.Ramirez, 3B2-5114
    Kyle Manzardo logo4K.Manzardo, DH1-3111
    Carlos Santana logo5C.Santana, 1B0-4000
    Gabriel Arias logo6G.Arias, 2B1-4000
    Gabriel Arias logo6G.Arias, SS1-4000
    Angel Martinez logo7A.Martinez, CF2-4100
    Bo Naylor logo8B.Naylor, C0-4000
    Brayan Rocchio logo9B.Rocchio, SS2-2101
    Daniel Schneemann logo9D.Schneemann, PR0-0000
    Daniel Schneemann logo9D.Schneemann, 2B0-0000

    Yankees vs. Guardians Odds Comparison

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    Yankees at Guardians Team Totals

    MatchupOverUnder
    Yankees
    3-4
    o4.5-109
    u4.5-121
    Guardians
    1-2
    o3.5-142
    u3.5+109