Yankees vs. Guardians Odds & Betting Predictions - April 21, 2025

Yankees at Guardians

10:10 pm • YES

New York Yankees

17-11

4 - 6

Cleveland Guardians

15-12

pitcher		team	era	w-l
G.Williams			4.15	2-1
C.Schmidt			5.52	0-1

MatchupOpenSpreadTotalMoneyline
Yankees 17-11	-1.5	-1.5+131	o8.5-122	-130
Guardians 15-12	u8.5	+1.5-155	u8.5+102	+110

Monday 10:10 p.m.

April 21, 2025

Progressive FieldCleveland

NYY -120 (Live)

1.2u

K.Manzardo o0.5 HR+525

0.53u

C.Schmidt o4.5 Ks+110

0.55u

#Tailing @The_Oddsmaker

C.Schmidt o4.5 Ks+100

Proj closer to -120, but has a Priority Score of +21.7

CLE +113

2.26u

#BQ

NYY -124

NYY -128

2.56u

NYY -121

1.21u

Over 8.5-115

CLE +100

K.Manzardo o0.5 HR+575

2.88u

NYY -120

1.2u

J.Ramirez o0.5 HR+520

1.04u

Day 2

C.Schmidt o4.5 Ks-102

0.98u

Bumping his pitch count projection to 85 tonight, which puts his strikeout projection at 5.01. Pitchers in that range for me have gone over 4.5 strikeouts 55% of the time.

Over 8-128

A.Judge o0.5 HR+250

0.4u

5.63% ev

Over 8.5+100

0.5u

Bet to -105

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No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 6-9 in their road games against the spread
The totals have gone OVER in 3 of Guardians' last 5 games
The totals have gone OVER in 6 of Guardians' 12 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	12-15	6-6	6-9	6-3	6-11
Yankees	15-13	10-5	5-8	14-9	1-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	14-11-2	6-6	8-5-2	5-4	9-6-2
Yankees	13-13-2	8-7	5-6-2	11-11-1	2-2-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	15-12	8-4	7-8	8-1	7-10
Yankees	17-11	10-5	7-6	16-7	1-4

date	opponent	score	spread	over/under	moneyline
Apr 20th	@PIT	W 5-4	-1.5 L	O 8	CLE +105
Apr 19th	@PIT	W 3-0	+1.5 W	U 8	CLE +145
Apr 18th	@PIT	W 10-7	-1.5 W	O 9	CLE -130
Apr 17th	@BAL	L 2-6	+1.5 L	U 8	BAL +116
Apr 16th	@BAL	L 1-9	+1.5 L	O 8	BAL +109

Shane Bieber
P
Bieber is out with elbow
Out
Slade Cecconi
P
Cecconi is out with oblique
Out
John Means
P
Means is out with elbow
Out
Lane Thomas
OF
Thomas is out with wrist
Out
David Fry
C
Fry is out with elbow
Out

Gerrit Cole
P
Cole is out for season with elbow
Out for Season
DJ LeMahieu
IF
LeMahieu is out with calf
Out
Giancarlo Stanton
DH
Stanton is out with elbow
Out
Luis Gil
P
Gil is out with back
Out
JT Brubaker
P
Brubaker is out with ribs
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RC.Schmidt, P	80	4	7	5
RY.Gomez, P	46	3	0	1
LR.Yarbrough, P	13	1	0	0

HITTERS	H-AB	R	HR	RBI
1A.Wells, C	0-5	0	0	0
2A.Judge, DH	1-4	0	0	0
3C.Bellinger, CF	1-4	0	0	0
4P.Goldschmidt, 1B	2-3	1	0	0
5J.Chisholm, 2B	1-4	1	1	2
6A.Volpe, SS	1-3	1	0	0
7J.Dominguez, LF	1-4	1	1	2
8P.Reyes, RF	1-3	0	0	0
8B.Rice, PH	0-1	0	0	0
9O.Cabrera, 3B	2-4	0	0	0

PITCHER	PC	IP	K	ER
RG.Williams, P	104	6.1	8	2
RP.Sewald, P	19	1.1	1	2
LJ.Cantillo, P	9	0.1	1	0
RC.Smith, P	11	1	2	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	2-4	2	0	0
2N.Jones, RF	0-3	0	0	0
2J.Noel, PH	0-1	0	0	0
2J.Noel, RF	0-1	0	0	0
3J.Ramirez, 3B	2-5	1	1	4
4K.Manzardo, DH	1-3	1	1	1
5C.Santana, 1B	0-4	0	0	0
6G.Arias, 2B	1-4	0	0	0
6G.Arias, SS	1-4	0	0	0
7A.Martinez, CF	2-4	1	0	0
8B.Naylor, C	0-4	0	0	0
9B.Rocchio, SS	2-2	1	0	1
9D.Schneemann, PR	0-0	0	0	0
9D.Schneemann, 2B	0-0	0	0	0