Yankees vs. Guardians Odds & Betting Predictions - April 21, 2025
Yankees at Guardians
10:10 pm • YESStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.06 | 12-5 | ||
![]() | 3.32 | 4-4 |
Yankees at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Yankees 3-4 | -1.5 | -1.5+131 | o8.5-122 | -130 |
Guardians 1-2 | u8.5 | +1.5-155 | u8.5+102 | +110 |

Progressive FieldCleveland
Yankees vs. Guardians Expert Picks
The Degenerates
Last 30d: 83-82-2 (-5.4u)
NYY -120 (Live)
1.2u
Top Shelf Action 🥃
Last 30d: 161-164-13 (+9.2u)
K.Manzardo o0.5 HR+525
0.53u
Gilles Gallant
Last 30d: 22-60-0 (-1.4u)
C.Schmidt o4.5 Ks+110
0.55u
#Tailing @The_Oddsmaker
Sean Koerner
Last 30d: 41-30-0 (+5.5u)
C.Schmidt o4.5 Ks+100
1u
Proj closer to -120, but has a Priority Score of +21.7
Boomer Betz
Last 30d: 194-181-10 (+25.3u)
CLE +113
2.26u
#BQ
Austin Pendergrass
Last 30d: 32-46-0 (-13.7u)
NYY -124
1u
Shady Biev
Last 30d: 0-0-0 (+0.0u)
NYY -128
2.56u
Royals Props
Last 30d: 40-42-2 (-7.4u)
NYY -121
1.21u
PX
💰🦡 Jake
Last 30d: 87-105-4 (-12.9u)
Over 8.5-115
1u
Steak Friend
Last 30d: 0-0-0 (+0.0u)
CLE +100
1u
Grant Neiffer
Last 30d: 36-89-10 (-5.4u)
K.Manzardo o0.5 HR+575
2.88u
Greg DiNardo
Last 30d: 0-0-0 (+0.0u)
NYY -120
1.2u
Matt DiLeo
Last 30d: 54-39-5 (+8.0u)
C.Schmidt o14.5 Outs-135
1u
Boomer Betz
Last 30d: 194-181-10 (+25.3u)
J.Ramirez o0.5 HR+520
1.04u
Day 2
Capper Central
Last 30d: 82-72-0 (+2.4u)
Over 8-128
1u
Top Shelf Action 🥃
Last 30d: 161-164-13 (+9.2u)
A.Judge o0.5 HR+250
0.4u
5.63% ev

Sean Zerillo
Last 30d: 63-58-1 (+1.6u)
Over 8.5+100
0.5u
Bet to -105
Yankees vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Yankees vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 1-4 in their last 5 games against the spread
- Guardians are 47-34 in their road games against the spread
- The totals have gone OVER in 2 of Guardians' last 5 games
- The totals have gone OVER in 37 of Guardians' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Yankees Injury Updates

Guardians Injuries

Yankees Injuries
- Gerrit ColeSP
Cole is out for season with elbow
Out for Season
Yankees vs. Guardians Box Score
Yankees Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 80 | 4 | 7 | 5 | |
![]() | 46 | 3 | 0 | 1 | |
![]() | 13 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-5 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 2 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 2 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 104 | 6.1 | 8 | 2 | |
![]() | 19 | 1.1 | 1 | 2 | |
![]() | 9 | 0.1 | 1 | 0 | |
![]() | 11 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 2 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 2-5 | 1 | 1 | 4 |
![]() | 1-3 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-2 | 1 | 0 | 1 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
Yankees vs. Guardians Odds Comparison
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Yankees at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Yankees 3-4 | o4.5-109 | u4.5-121 |
Guardians 1-2 | o3.5-142 | u3.5+109 |
































