Yankees vs. Guardians Odds & Betting Predictions - April 21, 2025

Yankees at Guardians

10:10 pm • YES

New York Yankees

67-57

4 - 6

Cleveland Guardians

64-60

pitcher		team	era	w-l
G.Williams			3.24	8-4
C.Schmidt			3.32	4-4

MatchupOpenSpreadTotalMoneyline
Yankees 67-57	-1.5	-1.5+131	o8.5-122	-130
Guardians 64-60	u8.5	+1.5-155	u8.5+102	+110

Monday 10:10 p.m.

April 21, 2025

Progressive FieldCleveland

NYY -120 (Live)

1.2u

K.Manzardo o0.5 HR+525

0.53u

C.Schmidt o4.5 Ks+110

0.55u

#Tailing @The_Oddsmaker

C.Schmidt o4.5 Ks+100

Proj closer to -120, but has a Priority Score of +21.7

CLE +113

2.26u

#BQ

NYY -124

NYY -128

2.56u

NYY -121

1.21u

Over 8.5-115

CLE +100

K.Manzardo o0.5 HR+575

2.88u

NYY -120

1.2u

J.Ramirez o0.5 HR+520

1.04u

Day 2

C.Schmidt o4.5 Ks-102

0.98u

Bumping his pitch count projection to 85 tonight, which puts his strikeout projection at 5.01. Pitchers in that range for me have gone over 4.5 strikeouts 55% of the time.

Over 8-128

A.Judge o0.5 HR+250

0.4u

5.63% ev

Over 8.5+100

0.5u

Bet to -105

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See more MLB Coverage

No props found

MLB Public Betting

Guardians are 1-4 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 36-27 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 31 of Guardians' 62 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	64-61	28-34	36-27	27-28	37-31
Yankees	56-69	33-29	23-40	47-59	8-10

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	56-64-5	31-29-2	25-35-3	29-25-1	26-38-4
Yankees	58-63-4	26-35-1	32-28-3	49-55-2	8-8-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	64-61	31-31	33-30	34-21	30-38
Yankees	68-57	37-25	31-32	60-46	7-11

date	opponent	score	spread	over/under	moneyline
Apr 20th	@PIT	W 5-4	-1.5 L	O 8	CLE +105
Apr 19th	@PIT	W 3-0	+1.5 W	U 8	CLE +145
Apr 18th	@PIT	W 10-7	-1.5 W	O 9	CLE -130
Apr 17th	@BAL	L 2-6	+1.5 L	U 8	BAL +116
Apr 16th	@BAL	L 1-9	+1.5 L	O 8	BAL +109

Ben Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

Gerrit Cole
SP
Cole is out for season with elbow
Out for Season
Austin Slater
LF
Slater is out with hamstring
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RC.Schmidt, P	80	4	7	5
RY.Gomez, P	46	3	0	1
LR.Yarbrough, P	13	1	0	0

HITTERS	H-AB	R	HR	RBI
1A.Wells, C	0-5	0	0	0
2A.Judge, DH	1-4	0	0	0
3C.Bellinger, CF	1-4	0	0	0
4P.Goldschmidt, 1B	2-3	1	0	0
5J.Chisholm, 2B	1-4	1	1	2
6A.Volpe, SS	1-3	1	0	0
7J.Dominguez, LF	1-4	1	1	2
8P.Reyes, RF	1-3	0	0	0
8B.Rice, PH	0-1	0	0	0
9O.Cabrera, 3B	2-4	0	0	0

PITCHER	PC	IP	K	ER
RG.Williams, P	104	6.1	8	2
RP.Sewald, P	19	1.1	1	2
LJ.Cantillo, P	9	0.1	1	0
RC.Smith, P	11	1	2	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	2-4	2	0	0
2N.Jones, RF	0-3	0	0	0
2J.Noel, PH	0-1	0	0	0
2J.Noel, RF	0-1	0	0	0
3J.Ramirez, 3B	2-5	1	1	4
4K.Manzardo, DH	1-3	1	1	1
5C.Santana, 1B	0-4	0	0	0
6G.Arias, 2B	1-4	0	0	0
6G.Arias, SS	1-4	0	0	0
7A.Martinez, CF	2-4	1	0	0
8B.Naylor, C	0-4	0	0	0
9B.Rocchio, SS	2-2	1	0	1
9D.Schneemann, PR	0-0	0	0	0
9D.Schneemann, 2B	0-0	0	0	0