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Athletics vs Astros Prediction, Pick, MLB Odds for Friday, June 5

Athletics vs Astros Prediction, Pick, MLB Odds for Friday, June 5 article feature image
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Photo Credit: Matt Marton-Imagn Images
Pictured: Shea Langeliers celebrates with Tyler Soderstrom and Henry Bolte

The Houston Astros host the Athletics on June 5, 2026. First pitch from Daikin Park is scheduled for 8:10 p.m. EDT. The game will be broadcast on NBCS-CA.

The Athletics are favored by -110 on the moneyline and by -1.5 on the run line. The Astros are -110 on the moneyline and +1.5 on the run line. The total is set at 9 runs.

Find my MLB picks and Athletics vs Astros prediction below, as well as probable pitchers, weather report, and more.


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Athletics vs Astros Prediction

  • Athletics vs Astros Pick: Shea Langeliers Over 0.5 Home Runs (+279, DraftKings)

My Athletics vs Astros best bet is on Langeliers to record 1+ home runs. Make sure to find the best odds by checking our live MLB odds page.


Athletics vs Astros Odds

Athletics Logo
June 5, 2026
8:10 p.m. EDT
NBCS-CA
Astros Logo
Athletics Odds
SpreadTotalMoneyline
-1.5
-176
9
-102o / -118u
-110
Astros Odds
SpreadTotalMoneyline
+1.5
+148
9
-102o / -118u
-110
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Athletics vs Astros moneyline: Athletics -110, Astros -110
  • Athletics vs Astros over/under: 9 (-102o / -118u)
  • Athletics vs Astros spread: Athletics -1.5 (+148), Astros +1.5 (-176)

Athletics vs Astros Probable Pitchers

Jack PerkinsStatPeter Lambert
2-2W-L4-4
0.7fWAR (FanGraphs)0.9
5.46 / 3.14ERA / xERA3.77 / 3.86
2.60 / 3.82FIP / xFIP3.43 / 4.34
20.8K-BB%11.6
40.5GB%41.3
.333BABIP.267
102Stuff+90
106Location+99

Athletics vs Astros MLB Betting Preview

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Athletics vs Astros Pick, Betting Analysis

Peter Lambert has been good this season, but he's due for some heavy negative regression when it comes to power suppression. He's been a big plus for right-handed power in his career, allowing 1.62 HR/9.

This ballpark is good for right-handed power, and Shea Langeliers has been one of the best home run hitters in the league since last season's All-Star break.

I have the true odds here around +250, making this a great bet.

Pick: Shea Langeliers Over 0.5 Home Runs (+279, DraftKings)


Athletics vs Astros Weather


Get the latest coverage on MLB Weather.
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About the Author
Grant NeifferVerified Action Expert

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