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We have a full 4-game slate on Wednesday, and I’m bringing you four bangers across three MLB playoff matchups: Guardians vs. White Sox (4:00 p.m. ET), Dodgers vs. Braves (6:00 p.m. ET), and Brewers vs. Padres (10:00 p.m. ET).
Read on for my 4 MLB Home Run Picks on Wednesday.
MLB Home Run Picks Today
In the table below, you'll find each of Grant Neiffer's top home run prop picks from today's slate of games. Click on any pick or team logo to navigate to a specific bet discussed in this article and download the Action Network app for more picks and analysis.
| Game | Time (ET) | Pick |
|---|---|---|
  | 4:00 PM | |
  | 6:00 PM | |
  | 10:00 PM | |
| 10:00 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
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Guardians vs White Sox Prediction, Pick
This looks like it will be a bullpen game for Cleveland, but these odds aren't high enough on Munetaka Murakami, so I don't care.
The weather should be good for lefty power, with wind blowing out to right field. The Guardians bullpen has been middle of the pack this season in allowing homers, and Murakami is one of the league's best HR hitters.
I have the true odds on the White Sox 1B at around +350.
Pick: Munetaka Murakami Home Run
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Dodgers vs Braves Prediction, Pick
This isn't a bad spot, and these odds are far too high.
Braves starter Tyler Mahle has been an average matchup for righty power this season, but he's a reverse-splits pitcher and grades out as a plus matchup for righty power.
Mookie Betts isn't the same hitter he used to be, but I have the true odds for the Dodgers SS at around +600.
Pick: Mookie Betts Home Run
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Brewers vs Padres Prediction, Pick
This is probably my favorite bet of the day. Walker Buehler has been a gas can for righty power this season, allowing a high 1.56 HR/9.
The Padres bullpen is worse with Mason Miller on paternity leave, and Jackson Chourio is a great home run hitter.
I have the true odds for Chourio at around +420.
Pick: Jackson Chourio Home Run
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Brewers vs Padres Prediction, Pick
This is a good spot, and these odds are far too high.
Chad Patrick is getting the start for the Brewers, and he's been a plus matchup this season for lefty power (1.27 HR/9) and grades out as an even better matchup.
I have the true odds for Jackson Merrill at around +480.
Pick: Jackson Merrill Home Run
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