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Orioles vs Cardinals Prediction, Odds & Home Run Pick for Today’s Game — 8/26

Orioles vs Cardinals Prediction, Odds & Home Run Pick for Today’s Game — 8/26 article feature image
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Aug 25, 2026; St. Louis, Missouri, USA; Baltimore Orioles first baseman Pete Alonso (25) flips his bat as he runs down the line after hitting a three run home run against the St. Louis Cardinals during the third inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

The St. Louis Cardinals host the Baltimore Orioles on August 26, 2026. First pitch from Busch Stadium is scheduled for 7:45 p.m. EDT. The game will be broadcast on CARD.

Find my MLB picks and Orioles vs Cardinals prediction below, as well as probable pitchers, weather report, and more.


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Orioles vs Cardinals Prediction

  • Orioles vs Cardinals Pick: Pete Alonso Home Run (17c, Kalshi)

Orioles vs Cardinals Odds


Orioles vs Cardinals MLB Preview

This isn't a great spot, but these odds more than make up for it.

Michael McGreevy has been good this season, but he has allowed only a 1.03 HR/9 to righties, which is below average.

The underlying numbers point toward a slight amount of negative regression, but he still grades out as an average matchup for righty power.

This ballpark is below average for power, but the weather should be well above average for hitting, with temps in the high-80s and wind blowing out at 6 MPH.

This spot is slightly above average for Alonso.

Pick: Pete Alonso Home Run (17c, Kalshi)

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About the Author
Grant NeifferVerified Action Expert

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