The Minnesota Twins host the Cleveland Guardians on July 8, 2026. First pitch from Target Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on MNNT.
The Twins are favored by -131 on the moneyline and by -1.5 on the run line. The Guardians are +110 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Guardians vs Twins prediction below, as well as probable pitchers, weather report, and more.
- Guardians vs Twins Pick: Chase DeLauter Over 1.5 Total Bases / Guardians F5 ML
My Guardians vs Twins best bet is a prop on Chase DeLauter and Cleveland to take the lead after the first five innings. Make sure to find the best odds by checking our live MLB odds page.
Guardians vs Twins Odds
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +155 | 8.5 -100o / -120u | +110 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -188 | 8.5 -100o / -120u | -131 |
- Guardians vs Twins moneyline: Guardians +110, Twins -131
- Guardians vs Twins over/under: 8.5 (-100o / -120u)
- Guardians vs Twins spread: Twins -1.5 (+155 ), Guardians +1.5 (-188)
Guardians vs Twins Probable Pitchers
| RHP Slade Cecconi (CLE) | Stat | LHP Connor Prielipp (MIN) |
|---|---|---|
| 4-6 | W-L | 2-5 |
| 0.9 | fWAR (FanGraphs) | 1.2 |
| 4.44 / 4.52 | ERA / xERA | 4.96 / 4.09 |
| 4.40 / 4.35 | FIP / xFIP | 3.64 / 4.15 |
| 10.4% | K-BB% | 15.4% |
| 46.4% | GB% | 41.7% |
| .307 | BABIP | .322 |
| 93 | Stuff+ | 102 |
| 101 | Location+ | 103 |
Guardians vs Twins MLB Betting Preview
The Twins will host the Guardians in the second of a three-game series at Target Field.
27-year-old righty Slade Cecconi will take the mound for the visiting Guardians, while Minnesota plans to send out rookie left-hander Connor Prielipp in a game we may see plenty of runs.
In Prielipp’s first 12 starts of his MLB career, he has had a very difficult time transitioning to the majors with a 4.96 ERA on the season thus far across 62 innings.
Given the Twins’ youngster’s lack of punch-out prowess ranking outside the top-100 amongst starting pitchers, Prielipp relies far too heavily on ground-outs in regard to his ability to retire opposing hitters.

Guardians vs Twins Pick, Betting Analysis
Per BARTOLO, Prielipp throws his four-seam fastball more than any other pitch in his arsenal at a whopping 29%, despite that pitch generating just a 12% strike-out rate and a 15% whiff-rate.
BARTOLO also suggests that Prielipp’s most-preferred pitch has been the least efficient in his entire arsenal, with hitters producing a .419 xwOBA.
I expect lefty slugger Chase DeLauter to have a massive night at the plate, given he excels versus high-velocity pitches and boasts a .365 AVG when facing left-handed pitchers.
I will be looking to back the Guardians’ DH to both exceed his 1.5 Total Base mark; I don't mind backing the Guardians on the first-five moneyline in this spot as Ceccioni’s form on the mound has been steadily improving with each start.
Picks:
- Chase DeLauter Over 1.5 Total Bases (+100 or Better)
- Guardians F5 ML (+100 or Better)





































