The San Diego Padres host the Houston Astros on August 7, 2026. First pitch from Petco Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on SCHN.
Find my MLB picks and Astros vs Padres prediction below, as well as probable pitchers, weather report, and more.
Astros vs Padres Prediction
Astros vs Padres Pick: Manny Machado Over 0.5 Home Runs (19c, Polymarket)
Astros vs Padres Polymarket MLB Odds
Astros vs Padres MLB Betting Preview
The spot here is a good one for Machado, and the odds are a bit too high.
Blanco has historically been an average matchup for righty power, but he's due for some negative regression and grades out as a plus matchup.
Machado has been bad this season, but the power has been great.
I have the true odds around +350, making this a great EV bet.
Pick: Manny Machado Over 0.5 Home Runs (19c, Polymarket)
