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Angels vs Astros Prediction, Pick, MLB Odds for Friday, March 27

Angels vs Astros Prediction, Pick, MLB Odds for Friday, March 27 article feature image
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Rhona Wise-Imagn Images. Pictured: Isaac Paredes

The Houston Astros host the Los Angeles Angels on March 27, 2026. First pitch from Daikin Park is scheduled for 8:15 p.m. ET. The game will be broadcast on Apple TV+.

The Astros are favored by -160 on the moneyline and by -1.5 on the run line. The Angels are +135 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Angels vs Astros prediction below, as well as probable pitchers, weather report, and more.


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Angels vs Astros Prediction

  • Angels vs Astros Pick: Isaac Paredes Home Run (+500)

My Angels vs Astros best bet is on Isaac Paredes to hit a homer tonight. Make sure to find the best odds by checking our live MLB odds page.


Angels vs Astros Odds

Angels Logo
Friday, March 27
8:15 p.m. ET
Apple TV+
Astros Logo
Angels Odds
SpreadTotalMoneyline
+1.5
-160
8.5
-115o / -105u
+135
Astros Odds
SpreadTotalMoneyline
-1.5
+135
8.5
-115o / -105u
-160
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo
  • Angels vs Astros spread: Angels +1.5 (-160), Astros -1.5 (+135)
  • Angels vs Astros over/under: 8.5 (-115o / -105u)
  • Angels vs Astros moneyline: Angels +135, Astros -160

Angels vs Astros Projected Starting Pitchers

LHP Yusei Kikuchi (LAA)2025 StatsRHP Mike Burrows (HOU)
7-11W-L2-4
2.5fWAR (FanGraphs)1.3
3.99 / 4.47ERA / xERA3.94 / 4.32
4.23 / 4.28FIP / xFIP4.00 / 3.86
1.42WHIP1.24
13.0K-BB%16.4
39.7GB%41.8
98Stuff+95
105Location+101

Angels vs Astros Preview, Prediction

The odds are far too high for Astros third baseman Isaac Paredes to hit a home run here.

Angels starter Yusei Kikuchi had an above-average year last season, but historically, he's been a gas can for righty power, allowing a massive 1.61 HR/9.

Paredes isn't a huge power guy, but he pulls the ball at the highest rate in the league, and that plays great over in Houston with the Crawford boxes.

I have the true odds on Paredes under +500, making this a great EV bet.

Pick: Isaac Paredes Home Run (+500, BetMGM)

Playbook

Angels vs Astros Weather


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About the Author
Grant NeifferVerified Action Expert

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