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Padres vs Diamondbacks Prediction, Pick, MLB Odds for Sunday, April 26

Padres vs Diamondbacks Prediction, Pick, MLB Odds for Sunday, April 26 article feature image
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David Frerker-Imagn Images. Pictured: Padres second baseman Jake Cronenworth and right fielder Fernando Tatis Jr.

The Arizona Diamondbacks host the San Diego Padres on April 26, 2026. First pitch from Estadio Alfredo Harp Helu is scheduled for 4:05 p.m. ET. The game will be broadcast on SDPA.

The Padres are favored by -134 on the moneyline and by -1.5 on the run line. The Diamondbacks are +114 on the moneyline and +1.5 on the run line. The total is set at 15 runs.

Find my MLB picks and Padres vs Diamondbacks prediction below, as well as probable pitchers, weather report, and more.


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Padres vs Diamondbacks Prediction

  • Padres vs Diamondbacks Pick: Jake Cronenworth Over 0.5 RBI (+115)

My Padres vs Diamondbacks best bet is on Jake Cronenworth to record one or more RBIs today. Make sure to find the best odds by checking our live MLB odds page.


Padres vs Diamondbacks Odds

Padres Logo
Sunday, April 26
4:05 p.m. ET
SDPA
Diamondbacks Logo
Padres Odds
SpreadTotalMoneyline
-1.5
+100
15
-110o / -110u
-134
Diamondbacks Odds
SpreadTotalMoneyline
+1.5
-120
15
-110o / -110u
+114
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Padres vs Diamondbacks moneyline: Padres -134, Diamondbacks +114
  • Padres vs Diamondbacks over/under: 15 (-110o / -110u)
  • Padres vs Diamondbacks spread: Padres -1.5 (+100), Diamondbacks +1.5 (-120)

Padres vs Diamondbacks Probable Pitchers

RHP Michael King (SD)StatRHP Ryne Nelson (ARI)
3-1W-L1-2
0.5fWAR (FanGraphs)0.1
2.28 / 4.23ERA / xERA6.97 / 5.15
3.69 / 4.62FIP / xFIP5.04 / 4.60
10.7K-BB%11.5
43.9GB%31.8
.239BABIP.270
95Stuff+109
90Location+98

Padres vs Diamondbacks MLB Betting Preview

Action PRO projects Padres 2B Jake Cronenworth for 0.69 runs batted-in in their game against the Diamondbacks today, giving us a solid 12.8% edge against the market when compared to his current prop line of over/under 0.5, which is good enough to mark the Over with a B+ grade in our system.

San Diego will go against Ryne Nelson, who has a 6.97 ERA and is coming off a horrible and extremely brief outing against the Blue Jays, allowing eight earned runs in just 1/3 of an inning.

Cronenworth just had his best week at the plate this season, with a .675 OPS, and although he isn't a run producer, if the Padres score a bunch of runs today, he could get involved.

At plus money, let's back him tonight against Nelson and the Diamondbacks.

Pick: Jake Cronenworth Over 0.5 RBI (+115, FanDuel)

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