Padres vs Mariners Prediction, Pick, Odds for Wednesday, August 27

Padres vs Mariners Prediction, Pick, Odds for Wednesday, August 27 article feature image
Credit:

Jonathan Hui-Imagn Images.
Pictured: Yu Darvish.

The Seattle Mariners host the San Diego Padres on August 27, 2025. First pitch from T-Mobile Park is scheduled for 4:10 p.m. EDT; the game will be broadcast on ROOT Sports NW.

Find my MLB betting preview and Padres vs Mariners prediction below, as well as probable pitchers, betting trends, injury reports and more.

The Mariners enter this series finale as -140 favorites, as the road Padres are +115 underdogs.

Quickslip

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My Padres vs Mariners Prediction

  • Padres vs Mariners picks: Padres ML (play to +100)

My Padres vs Mariners best bet is Padres ML (play to +100). Make sure to find the best odds by checking our live MLB odds page.


Padres vs Mariners Odds

Padres Logo
Wednesday, Aug 27
4:10 p.m. ET
ROOT Sports NW
Mariners Logo
Padres Odds
SpreadTotalMoneyline
+1.5
-200
7.5
-118o / -102u
+115
Mariners Odds
SpreadTotalMoneyline
-1.5
+165
7.5
-118o / -102u
-140
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Sean Paul’s Padres vs Mariners Preview

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San Diego Padres Betting Preview

I certainly have my questions about the Padres' rotation, and a lot of it centers around Yu Darvish. The veteran hurler tossed a gem in his last outing, holding the Dodgers to one run with one hit over six innings.

While Darvish is pitching to a 5.09 ERA, his 3.75 xERA and 4.58 FIP signal positive regression.

The real key for Darvish is limiting the long-ball, as he surrenders a concerning 1.44 HR/9. That doesn’t mean one or two solo homers can totally derail a Darvish outing. Just look at his start versus the Giants, where he allowed one run, and the most recent start against the Dodgers.

You can look at Darvish’s age and his ERA and think “yeah, this guy is washed”. But I’d push back on that sentiment. Sure, Darvish is past his prime, but he ranks in the 75th percentile or better in xBA, average exit velo, and hard-hit rate. That’s not the sign of someone who’s totally washed up.

The Padres made plenty of moves at the deadline. Of course, adding Mason Miller was the notable one. But the additions of Ramon Laureano and Ryan O’Hearn totally revitalized a once reeling Padres offense. Since the deadline, San Diego has the ninth-best wRC+ (112), with Laureano leading the team with a 168.

If you told me the Padres would return to being a top-10 offense without Manny Machado and Fernando Tatis Jr. going ballistic, I wouldn’t believe you. But here we are. That should make you believe in this San Diego offense being this good, if not better, in the season's final month.

Lastly, if Darvish can pitch a strong five innings, the Padres should have the clear advantage with their elite bullpen. No better group of pen arms exists than that of the Padres. The five relievers on one team that could close for other teams with Jason Adam, Jeremiah Estrada, Adrian Morejon, Miller, and Robert Suarez.


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Seattle Mariners Betting Preview

Bryan Woo is one of the best pitchers on the team with the best rotation in baseball. Woo boasts a dazzling 2.94 ERA with a slightly worse 3.08 xERA and 3.61 FIP. He's gone from a no-name prospect to one of the best pitchers in MLB.

Here's why I don't foresee Woo having his best outing versus the Padres. He's a heavy fastball usage pitcher that often lives up in the zone and hunts for strikeouts. Woo punched out 7+ hitters in four straight outings, and he's tallied over 9.00 K/9 this year. But that won't happen against this Padres team that rarely swings and misses. The Mariners hurler will need to be more creative to get out San Diego's contact-oriented lineup.

I'm not saying Woo will allow five runs or anything. But this isn't an easy matchup for him based on how he gets outs and how the Padres offense operates.

The Mariners' offense is the polar opposite of the Padres. Seattle has built its lineup around power and strikeouts, hitting the 7th most homers in August to date, while striking out the sixth most. In all, it's led to the Mariners placing 13th in wRC+ this month.

After adding Eugenio Suarez, the Mariners are the streakiest lineup in the league. Suarez is very streaky, as are Julio Rodriguez and Randy Arozarena. So, when the good times come for that trio — and of course — Cal Raleigh, things will be good in Seattle. When they aren't going well, things could get ugly. Suarez and Arozarena are each hitting below .200 this month, but J-Rod is dominating, posting a 156 wRC+.


Padres vs Mariners Prediction, Betting Analysis

I'll have to take the plus money with San Diego here. The Mariners have the pitching advantage with Woo over Darvish, but I don't think the gap is as big as the numbers say. Darvish is due for some better days and the bullpen advantage gives the Padres a slight edge in the pitching department.

Woo could get stung if he tries to get swings-and-misses up in the zone since San Diego doesn't swing and miss much. That could lead to some mistake pitches and an advantage for the Padres.

Go with San Diego here.

Pick: Padres ML (play to +100)

Padres vs Mariners Projected Starting Pitchers

RHP Yu Darvish (SDP)StatRHP Bryan Woo (SEA)
3-3W-L11-7
0.3fWAR (FanGraphs)3.0
5.36/3.75ERA /xERA2.94/3.08
4.58/4.25FIP / xFIP3.61/3.48
1.10WHIP0.94
2.8K-BB%5.3
40.8GB%39.8
99Stuff+104
98Location+110

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About the Author
Sean is a contributor for the Action Network college basketball and baseball verticals, focusing on bringing insightful, in-depth betting analysis. Sean started his writing career talking about college hoops, with a strong focus on mid-major hoops, which he still covers.

Follow Sean Paul @seanpaulcbb on Twitter/X.

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