Giants vs Nationals Prediction, Pick, Odds for Friday, May 23

Giants vs Nationals Prediction, Pick, Odds for Friday, May 23 article feature image
Credit:

Credit: Imagn Images. Pictured: San Francisco Giants SP Landen Roupp.

The Washington Nationals host the San Francisco Giants on May 23, 2025. First pitch from Nationals Park is scheduled for 6:45 p.m. EDT; the game will be broadcast on NBCS-BA.

Read our Giants vs Nationals prediction and MLB player prop pick below.

Quickslip

Header First Logo
Header Second Logo

My Giants vs Nationals Prediction

  • Giants vs Nationals Pick: Landen Roupp Under 4.5 Strikeouts (-135, BetMGM)

My Giants vs Nationals best bet is on Landen Roupp's strikeout total. Check our live MLB odds page to find the best odds.


Giants vs Nationals Odds

Giants Logo
May 23, 2025
6:45 p.m. EDT
NBCS-BA
Nationals Logo
Giants Odds
SpreadTotalMoneyline
-1.5
+165
8
-100o / -120u
-102
Nationals Odds
SpreadTotalMoneyline
+1.5
-200
8
-100o / -120u
-118
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo

Alex Kolodziej’s Giants vs Nationals Preview

Header First Logo

San Francisco Giants Player Prop

Our Action PRO Model projects Giants starting pitcher Landen Roupp for 3.7 strikeouts in Friday’s game against the Nationals, providing around a 10% edge over the current market price (4.5, juiced to the under).

Roupp excels at limiting hard contact but lacks elite swing-and-miss stuff, mainly because he relies on a low-velo fastball and a slightly-above-average curveball.

The Nationals aren’t easy to strike out, as they boast the 11th-lowest strikeout rate among MLB lineups (21.4%), a mark that decreases slightly against right-handed pitchers (20.4%).

Nationals Park ranks 19th among all MLB parks in Statcast’s Strikeout Factor (98), as it tends to play more like a hitter’s park than not (103 Park Factor overall, seventh).

Pick: Landen Roupp Under 4.5 Strikeouts (-135, BetMGM)


Giants vs Nationals Betting Trends


Giants vs Nationals Weather


Get the latest coverage on MLB Weather.
About the Author
Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

Follow Alex Kolodziej @KolodziejAlex on Twitter/X.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.