The St. Louis Cardinals host the Seattle Mariners on April 26, 2026. First pitch from Busch Stadium is scheduled for 2:15 p.m. EDT. The game will be broadcast on CARD.
The Mariners are favored by -130 on the moneyline and by -1.5 on the run line. The Cardinals are +108 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Mariners vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
Mariners vs Cardinals Prediction
- Mariners vs Cardinals Pick: Michael McGreevy Over 16.5 Pitching Outs (-107)
My Mariners vs Cardinals best bet is on Michael McGreevy to record over 16.5 pitching outs. Make sure to find the best odds by checking our live MLB odds page.
Mariners vs Cardinals Odds
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +124 | 8.5 -115o / -105u | -130 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -149 | 8.5 -115o / -105u | +108 |
- Mariners vs Cardinals moneyline: Mariners -130, Cardinals +108
- Mariners vs Cardinals over/under: 8.5 (-115o / -105u)
- Mariners vs Cardinals spread: Mariners -1.5 (+124), Cardinals +1.5 (-149)
Mariners vs Cardinals Probable Pitchers
| RHP Emerson Hancock (SEA) | Stat | RHP Michael McGreevy (STL) |
|---|---|---|
| 2-1 | W-L | 1-2 |
| 0.4 | fWAR (FanGraphs) | 0.2 |
| 2.83/3.88 | ERA / xERA | 3.29/6.65 |
| 3.99/3.12 | FIP / xFIP | 4.50/4.39 |
| 22.9% | K-BB% | 9.5% |
| 44.4% | GB% | 42.9% |
| .239 | BABIP | .198 |
| 106 | Stuff+ | 78 |
| 110 | Location+ | 110 |
Mariners vs Cardinals MLB Pick, Betting Analysis
The Cardinals are in a pickle right now. They used their entire bullpen in blowing yesterday's game, including a whopping 50 pitches from their closer.
They are also in just the third day of a stretch of 17 games in 17 days.
They absolutely need length from Michael McGreevy today regardless of how he is doing. If he is pitching well, they will gladly let him go. If he is getting knocked around, he may need to be a sacrificial arm for a day.
In either case, I think he is out there for at least 6 innings, and I will happily take the over on 16.5 pitching outs.
Pick: Michael McGreevy Over 16.5 Pitching Outs (-107)
