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Rays vs Phillies Prediction, Pick, MLB Odds for Friday, September 25

Rays vs Phillies Prediction, Pick, MLB Odds for Friday, September 25 article feature image
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Pictured: Philadelphia Phillies starting pitcher Cristopher Sanchez. (Credit: John Jones-Imagn Images)

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The Philadelphia Phillies host the Tampa Bay Rays on September 25, 2026. First pitch from Citizens Bank Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on RAYS.

The Phillies are favored by -175 on the moneyline and by -1.5 on the run line. The Rays are +145 on the moneyline and +1.5 on the run line. The total is set at 6.5 runs.

Find my MLB picks and Rays vs Phillies prediction below, as well as probable pitchers, weather report, and more.


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Rays vs Phillies Prediction

  • Rays vs Phillies Pick: F5 Under 3.5 (-118)

My Rays vs Phillies best bet is on the under total runs after the first five innings. Make sure to find the best odds by checking our live MLB odds page and download the Action Network app for more picks and analysis.


Rays vs Phillies Odds

Rays Logo
Friday, Sep 25
6:40 p.m. ET
RAYS
Phillies Logo
Rays Odds
SpreadTotalMoneyline
+1.5
-160
6.5
-118o / -102u
+145
Phillies Odds
SpreadTotalMoneyline
-1.5
+135
6.5
-118o / -102u
-175
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo
  • Rays vs Phillies moneyline: Rays +145, Phillies -175
  • Rays vs Phillies over/under: 6.5 (-118o / -102u)
  • Rays vs Phillies spread: Phillies -1.5 (+135), Rays +1.5 (-160)

Rays vs Phillies Probable Pitchers

Freddy Peralta (RHP, TBR)StatCristopher Sanchez (LHP, PHI)
9-11W-L18-6
1.8fWAR (FanGraphs)6.0
4.56/3.82ERA / xERA2.93/3.39
4.31/4.36FIP / xFIP2.80/2.68
13.0%K-BB%21.3%
38.6%GB%57.7%
.288BABIP.335
96Stuff+116
106Location+97

Rays vs Phillies MLB Betting Preview

This is another gross weather spot. Winds are blowing straight in and there's some rain in the forecast.

Cristopher Sanchez has had a few blips recently, mostly due to allowing a few more HRs than usual.

It's going to be tough to get one out at Citizens Bank Park tonight. Tampa Bay is 25th in OPS and 26th in wOBA vs. lefties since the start of August.

The Rays fixed Freddy Peralta. He's allowed 3 ERs in his last 5 starts.

It took a bit, but the pitch mix and location adjustments with Tampa Bay have led to tremendous results.

Peralta faces a Philly lineup that ranks dead last in wRC+ vs. righties over the past 30 days.

Pick: F5 Under 3.5 (-118)


Rays vs Phillies Weather


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About the Author
Charlie Wright • Staff Writer

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