The Athletics host the Houston Astros on September 24, 2026. First pitch from Sutter Health Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on NBCS-CA.
The Astros are favored by -161 on the moneyline and by -1.5 on the run line. The Athletics are +135 on the moneyline and +1.5 on the run line. The total is set at 10.5 runs.
Find my MLB picks and Astros vs Athletics prediction below, as well as probable pitchers, weather report, and more.
Astros vs Athletics Prediction
- Astros vs Athletics Pick: Christian Walker 1+ Home Runs (+420, Fanatics)
My Astros vs Athletics best bet is on Walker to record at least 1 home run. Make sure to find the best odds by checking our live MLB odds page and be sure to download the Action Network app for more picks and analysis.
Astros vs Athletics Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -117 | 10.5 -115o / -105u | -161 |
| Athletics Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -103 | 10.5 -115o / -105u | +135 |
- Astros vs Athletics moneyline: Astros -161, Athletics +135
- Astros vs Athletics over/under: 10.5 (-115o / -105u)
- Astros vs Athletics spread: Astros -1.5 (-103), Athletics +1.5 (-117)
Astros vs Athletics Probable Pitchers
| Peter Lambert | Stat | Mason Barnett |
|---|---|---|
| 8-10 | W-L | 1-4 |
| 2.5 | fWAR (FanGraphs) | -0.6 |
| 3.70 / 3.67 | ERA / xERA | 7.16 / 5.38 |
| 3.81 / 4.42 | FIP / xFIP | 6.78 / 5.22 |
| 14 | K-BB% | 6.8 |
| 36.2 | GB% | 35.3 |
| .276 | BABIP | .306 |
| 92 | Stuff+ | 95 |
| 100 | Location+ | 98 |
Astros vs Athletics MLB Betting Preview
Astros vs Athletics Pick, Betting Analysis
This is a great spot, and these odds are far too high. Mason Barnett has been completely crushed by righty power this season (3.15 HR/9), and while he's due for a lot of positive regression, he still grades out as a favorable matchup for righty power. This ballpark is one of the best in the league for power, and the weather should be great for hitting, with temps in the low-80s and wind blowing out at 6 mph. I have the true odds here around +350.
Pick: Christian Walker 1+ Home Runs (+420, Fanatics)
