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Mets vs Nationals Prediction, Pick, MLB Odds for Friday, September 25

Mets vs Nationals Prediction, Pick, MLB Odds for Friday, September 25 article feature image
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Pictured: Washington Nationals shortstop CJ Abrams. (Credit: Jeff Le-Imagn Images)

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The Washington Nationals host the New York Mets on September 25, 2026. First pitch from Nationals Park is scheduled for 6:45 p.m. EDT. The game will be broadcast on WPIX.

The Mets are favored by -136 on the moneyline and by -1.5 on the run line. The Nationals are +113 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Mets vs Nationals prediction below, as well as probable pitchers, weather report, and more.


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Mets vs Nationals Prediction

  • Mets vs Nationals Pick: CJ Abrams Home Run (+650; Play to +550 or Better)

My Mets vs Nationals best bet is on CJ Abrams to hit a homer. Make sure to find the best odds by checking our live MLB odds page and download the Action Network app for more picks and analysis.


Mets vs Nationals Odds

Mets Logo
Friday, Sep 25
6:45 p.m. ET
WPIX
Nationals Logo
Mets Odds
SpreadTotalMoneyline
-1.5
+123
8
-105o / -115u
-136
Nationals Odds
SpreadTotalMoneyline
+1.5
-149
8
-105o / -115u
+113
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Mets vs Nationals moneyline: Mets -136, Nationals +113
  • Mets vs Nationals over/under: 8 (-105o / -115u)
  • Mets vs Nationals spread: Mets -1.5 (+123), Nationals +1.5 (-149)

Mets vs Nationals Probable Pitchers

TBD (NYM)StatAndrew Alvarez (LHP, WSN)
—W-L2-6
—fWAR (FanGraphs)2.6
—ERA / xERA3.17/4.06
—FIP / xFIP3.13/3.67
—K-BB%13.1%
—GB%50.0%
—BABIP.289
—Stuff+95
—Location+100

Mets vs Nationals MLB Betting Preview

By Derek Carty

Editor's Note: This written best bet is a transcription from the latest episode of the Payoff Pitch podcast.

CJ Abrams to hit a home run is the play for this game. I like it down to +550.

We don't have an official Mets pitcher confirmed yet, but it's looking like it's probably going to be Justin Hageman.

Regardless of who it is, though, it's going to represent a really good matchup for a home run.

We're getting great value on Abrams, who is simply a better hitter than that price implies.

Pick: CJ Abrams Home Run (+650, DraftKings; Play to +550 or Better)


Mets vs Nationals Weather


Get the latest coverage on MLB Weather.

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