LA Galaxy vs. Columbus Odds & Betting Predictions - April 22, 2026

LA Galaxy at Columbus

11:30 pm

LA Galaxy

5-5-5

1

1 - 2

Columbus Crew

4-7-4

2

MatchupOpenSpreadTotalMoneyline
LA Galaxy 5-5-5	+1.5	+1.5-250	o3.5+130	+360
Columbus 4-7-4	u3.5	-1.5+182	u3.5-161	-155

location pin

Wednesday 11:30 p.m.

April 22, 2026

ScottsMiracle-Gro FieldColumbus, OH

MLS Public Betting

Columbus are 1-2 in their last 5 games.
Columbus are 1-4 in their last 5 games against the spread
Columbus are 1-6 in their road games against the spread
The totals have gone OVER in 3 of Columbus' last 5 games
The totals have gone OVER in 1 of Columbus' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Columbus	3-11-1	2-5	1-6-1	3-10	0-1-1
LA Galaxy	8-7	3-4	5-3	2-5	6-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Columbus	8-7	1-6	7-1	7-6	1-1
LA Galaxy	8-7	3-4	5-3	4-3	4-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Columbus	4-7	3-2-2	1-5-2	4-6-3	0-1-1
LA Galaxy	5-5	2-2-3	3-3-2	2-3-2	3-2-3

date	opponent	score	spread	over/under	moneyline
Apr 18th	@NE	L 1-2	-0.5 L	O 2.5	NE +123
Apr 12th	ORL	W 1-1	-1.5 L	U 3.5	ORL -232
Apr 4th	@ATL	W 3-1	-0.5 W	O 2.5	CLB +125
Mar 21st	@TOR	L 1-2	-0.5 L	O 2.5	TOR +125
Mar 14th	NSH	L 0-1	-0.5 L	U 2.5	NSH -165

E. Boateng
MID
Boateng is out with knock injury
Out

Douglas Costa
MID
Metatarsal Fracture
Out Indefinitely
R. Alessandrini
MID
MCL Knee Ligament Injury
Out Indefinitely
N. DePuy
DEF
DePuy is injured
Out Indefinitely

See more MLS Injuries

LA Galaxy

Columbus

5

Fouls

13

4

Shots

10

1

Corners

4

1

Offsides

1

0

Red Cards

0

1

Yellow Cards

0

1

Shots On Goal

5

41%

Possession Time

59%

LA Galaxy

Goalkeeping

Columbus

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MatchupOverUnder
LA Galaxy 5-5-5	N/A	N/A
Columbus 4-7-4	N/A	N/A