Louisville vs. Clemson Odds & Betting Predictions - February 28, 2026
Louisville at Clemson
7:00 pm • ESPN2Louisville at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Louisville 20-8 | -1.5 | -1.5-111 | o146.5-110 | -130 |
Clemson 20-8 | u145.5 | +1.5-109 | u146.5-110 | +110 |

Littlejohn ColiseumClemson
Louisville vs. Clemson Expert Picks
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 1-4 in their last 5 games.
- Clemson are 2-3 in their last 5 games against the spread
- Clemson are 9-3 in their road games against the spread
- The totals have gone OVER in 2 of Clemson' last 5 games
- The totals have gone OVER in 5 of Clemson' 16 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 16-12 | 7-9 | 9-3 | 13-12 | 3-0 | |
| 13-15 | 8-8 | 5-7 | 10-10 | 0-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 11-17 | 5-11 | 6-6 | 10-15 | 1-2 | |
| 10-18 | 5-11 | 5-7 | 8-12 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 20-8 | N/A | N/A | 20-5 | 0-3 | |
| 20-8 | N/A | N/A | 15-5 | 0-3 |
Last 5 Matchups
Louisville vs. Clemson Injury Updates

Louisville Injuries
- Mikel BrownG
Brown is probable with undisclosed
Probable

Clemson Injuries
- Zac FosterG
Foster is out for season with knee
Out for Season
- Trent SteinourF/C
Steinour is out with undisclosed
Out
Team Stats
29-61 (48%)
Field Goals
25-55 (45%)
16-21 (76%)
Free Throws
15-20 (75%)
11-32 (34%)
3P
8-24 (33%)
37.25
Rebounds
31.86
17.5
Assists
13
11.75
Turnovers
9
7.21
Steals
6.14
3.36
Blocks
2.64
18.46
Fouls
16.29
Louisville vs. Clemson Odds Comparison
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Louisville at Clemson Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 20-8 | N/A | N/A |
Clemson 20-8 | N/A | N/A |
