Fighting Illini vs. Hoosiers Odds & Betting Predictions - September 20, 2025
Fighting Illini at Hoosiers
11:30 pm • NBCFighting Illini at Hoosiers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Fighting Illini 5-3 | +3 | +6.5-110 | o51.5-110 | +200 |
Hoosiers 8-0 | u54.5 | -6.5-115 | u51.5-110 | -250 |

Memorial Stadium (Bloomington, IN)Bloomington
Fighting Illini vs. Hoosiers Expert Picks
Sandy Plashkes
Last 30d: 97-106-1 (-0.9u)
IU -6.5-120
1.83u
FTN Fantasy
Last 30d: 49-56-1 (-5.7u)
IU -6.5-115
0.87u
IU -3.5 (1H)-112
0.89u
IU -2.5 (1Q)-108
0.93u
Vegas Refund
Last 30d: 39-38-1 (-3.0u)
IU -6.5-115
1u
Capper Central
Last 30d: 79-72-0 (-7.0u)
ILL +7.5-125
1.25u
Hedging out. Same spot as Arkansas and Wisco that lost.

Sean Zerillo
Last 30d: 93-107-5 (+7.4u)
IU -6.5-115
0.25u
Will Brinson
Last 30d: 14-14-1 (+0.3u)
IU -6.5-115
1u
Mjaybrod
Last 30d: 86-113-1 (-19.8u)
IU -6.5-110
0.91u
Roll Snowman
Capper Central
Last 30d: 79-72-0 (-7.0u)
IU -6.5-115
1u
Dan Gaspar
Last 30d: 39-38-2 (-3.7u)
J.Bowick u32.5 Rec Yds-114
1.14u
Roger Goodell
Last 30d: 48-43-1 (+6.4u)
IU o29.5 Team Total-120
0.83u
Picks Office
Last 30d: 118-97-4 (+13.8u)
IU -6.5-105
0.95u
The Pick Don
Last 30d: 18-9-0 (+11.2u)
IU -6.5-114
1.5u
Bad #, but Illinois is living on borrowed time. There’s no reason this should be a top 10 team. Yes, they beat Duke 45-19, but that score was a poor reflection of the game itself. Duke dominated in the trenches and only lost because they shot themselves in the foot all night. Indiana won’t let Illinois off the hook. The Hoosiers will win this battle up front. Their offensive line is elite. This unit is a top five unit nationally, especially in pass protection. Illinois defensive line simply isn’t good enough for a team ranked this high. Their front seven sits just 37th in the country. Indiana’s O-line will control this game and give Fernando Mendoza all the time he needs. Speaking of Mendoza, I loved him at Cal. Landing him through the portal was a brilliant move. He’s legit, and he’s made this offense look flat out dominant. Indiana is averaging 52 points per game through three contests. Sure, you can question the strength of schedule, but they’ve handled everyone in front of them with ease. Defensively, they’re just as strong. Indiana boasts a top 15 front seven and gets to face an Illinois offensive line ranked outside the top 45. The Hoosiers pass rush should control the line of scrimmage. Against Duke, Illinois managed just 0.02 expected points per rush attempt, with only 15 successful runs on 38 tries. This offense has no rhythm, and I think they’re in real trouble today. I’m very high on Indiana this season and ready to sell on Illinois. My ratings have Indiana as the 14th best team in the nation and Illinois at 21st, despite what the AP poll says. Indiana went 8-0 at home last season and are a better team this season. I think the Hoosiers will win by more than a touchdown.
Ryan Sura
Last 30d: 94-102-1 (-5.9u)
ILL +7-120
1.2u
Collin Wilson
Last 30d: 82-65-1 (+12.7u)
IU o30 Team Total-111
0.5u
As mentioned on BBOC
Boomer Betz
Last 30d: 176-175-3 (+7.7u)
IU -4.5+100
1u
Fighting Illini vs. Hoosiers Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Fighting Illini vs. Hoosiers Public Betting Percentages
Betting Trends
- Hoosiers are 5-0 in their last 5 games.
- Hoosiers are 3-2 in their last 5 games against the spread
- Hoosiers are 1-1 in their road games against the spread
- The totals have gone OVER in 2 of Hoosiers' last 5 games
- The totals have gone OVER in 5 of Hoosiers' 6 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-3 | 4-2 | 1-1 | 3-3 | 1-0 | |
| 5-3 | 3-1 | 2-2 | 3-0 | 1-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-3 | 5-1 | 0-2 | 4-2 | 0-1 | |
| 5-3 | 1-3 | 4-0 | 2-1 | 3-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 8-0 | N/A | N/A | 6-0 | 1-0 | |
| 5-3 | N/A | N/A | 3-0 | 1-3 |
Last 5 Matchups
Team Stats
161
Total Yards
579
45
Total Plays
72
3.577777777777778
Yards Per Play
8.041666666666666
159
YDS
267
16/25
Comps/Atts
21/23
6.36
YPA
11.608695652173912
1/1
TDs/INTs
5/0
7/47
Sacks/Yards
2/14
4/23
Penalties/Yards
2/10
Fighting Illini vs. Hoosiers Odds Comparison
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Fighting Illini at Hoosiers Team Totals
MatchupOverUnder | ||
|---|---|---|
Fighting Illini 5-3 | o22.5-116 | u22.5-114 |
Hoosiers 8-0 | o29.5-116 | u29.5-114 |






