The Delaware Fightin' Blue Hens take on the Wake Forest Demon Deacons in Winston-Salem, North Carolina. Kickoff is set for 12:00 p.m. EST on ACC Network.
Wake Forest is favored by 17.5 points on the spread with a moneyline of -900. The total is set at 50.5 points.
Here’s my Delaware vs. Wake Forest prediction and college football picks for Saturday, November 22, 2025.
Delaware vs Wake Forest Prediction
- Delaware vs. Wake Forest Pick: Under 50.5
My Wake Forest vs. Delaware best bet is on the Under. Find the best line available on our live NCAAF odds page.
Delaware vs Wake Forest Odds
| Delaware Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+17.5 -110 | 50.5 -110o / -110u | +600 |
| Wake Forest Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-17.5 -110 | 50.5 -110o / -110u | -900 |
- Delaware vs Wake Forest point spread: Wake Forest -17.5 (-110), Delaware +17.5 (-110)
- Delaware vs Wake Forest over/under: 50.5 (-110o / -110u)
- Delaware vs Wake Forest moneyline: Delaware +600, Wake Forest -900
Delaware vs Wake Forest Preview
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
Home Fave Unders is a college football system built around the idea that strong home favorites often play in ways that reduce overall scoring.
In the regular season, when the home team is favored by 2.5 to 19.5 points, these matchups often turn into controlled games in which the favorite manages the pace and protects the lead rather than pushing for maximum points.
Weather conditions also support lower scoring, as humidity above 40% and wind speeds above 8 MPH make passing and kicking less efficient.
When public betting on the total leans heavily toward one side, especially the over, lines can become inflated even though the actual game script favors a more conservative outcome.
This combination of home team control, weather impact, and public bias creates a consistent edge for the under.
Pick: Under 50.5
