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Liberty vs Louisiana Tech Prediction, Pick, NCAAF Odds for Saturday, Nov. 22

Liberty vs Louisiana Tech Prediction, Pick, NCAAF Odds for Saturday, Nov. 22 article feature image
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Credit: Imagn Images. Pictured: Liberty Flames head football coach Jamey Chadwell.

The Liberty Flames take on the Louisiana Tech Bulldogs in Ruston, Louisiana. Kickoff is set for 3:00 p.m. EST on ESPN+.

Liberty is favored by 1.5 points on the spread with a moneyline of -120. The total is set at 45 points.

Here’s my Liberty vs. Louisiana Tech predictions and college football picks for Saturday, November 22, 2025.


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Liberty vs Louisiana Tech Prediction

  • Liberty vs. Louisiana Tech Pick: Liberty -1.5 (-105, bet365)

My Louisiana Tech vs. Liberty best bet is on the Flames to cover. Find the best line available on our live NCAAF odds page.


Liberty vs Louisiana Tech Odds

Liberty Logo
Saturday, Nov 22
3 p.m. ET
ESPN+
Louisiana Tech Logo
Liberty Odds
SpreadTotalMoneyline
-1.5
-105
45
-110o / -110u
-120
Louisiana Tech Odds
SpreadTotalMoneyline
+1.5
-115
45
-110o / -110u
+100
Odds via bet365. Get up-to-the-minute NCAAF odds here.
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  • Liberty vs Louisiana Tech point spread: Liberty -1.5 (-105), Louisiana Tech +1.5 (-115)
  • Liberty vs Louisiana Tech over/under: 44.5 (-110o / -110u)
  • Liberty vs Louisiana Tech moneyline: Liberty -120, Louisiana Tech +100

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Liberty vs Louisiana Tech Game Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams.

In the regular season of college football, sharp money often reveals itself when the percentage of total wagered dollars on a team far exceeds the percentage of individual bets placed.

This gap suggests that larger, more informed wagers are backing one side, while the public is leaning the other way.

When betting volume sits in a moderate range, the market is active enough to matter but not yet distorted by extreme public attention.

By aligning with the side attracting this disproportionate financial support, bettors can follow the influence of professionals who may have identified value before the broader market adjusts.

Pick: Liberty -1.5 (-105, bet365)

Playbook

Liberty vs Louisiana Tech Betting Trends



Liberty vs Louisiana Tech Weather


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