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Sam Houston vs Middle Tennessee Prediction, Pick, NCAAF Odds for Saturday, Nov. 22

Sam Houston vs Middle Tennessee Prediction, Pick, NCAAF Odds for Saturday, Nov. 22 article feature image
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Credit: Imagn Images. Pictured: Middle Tennessee QB Nicholas Vattiato.

The Sam Houston State Bearkats take on the Middle Tennessee Blue Raiders in Murfreesboro, Tennessee. Kickoff is set for 3:00 p.m. EST on ESPN+.

Middle Tennessee is favored by 7 points on the spread with a moneyline of -260. The total is set at 54 points.

Here’s my Sam Houston vs. Middle Tennessee prediction and college football picks for Saturday, November 22, 2025.


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Sam Houston vs Middle Tennessee Prediction

  • Sam Houston vs. Middle Tennessee Pick: Under 54 (-110, bet365)

My Middle Tennessee vs. Sam Houston best bet is on the Under. Find the best line available on our live NCAAF odds page.


Sam Houston vs Middle Tennessee Odds

Sam Houston Logo
Saturday, Nov 22
3 p.m. ET
ESPN+
Middle Tennessee Logo
Sam Houston Odds
SpreadTotalMoneyline
+7
-110
54
-110o / -110u
+210
Middle Tennessee Odds
SpreadTotalMoneyline
-7
-110
54
-110o / -110u
-260
Odds via bet365. Get up-to-the-minute NCAAF odds here.
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  • Sam Houston vs Middle Tennessee point spread: Middle Tennessee -7 (-110), Sam Houston +7 (-110)
  • Sam Houston vs Middle Tennessee over/under: 54 (-110o / -110u)
  • Sam Houston vs Middle Tennessee moneyline: Sam Houston +210, Middle Tennessee -260

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Sam Houston vs Middle Tennessee Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams.

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Evan Abrams – Early Unranked Unders
the game is played during the Regular season
betting on the Under
the home team's rank is between 0 and 0
the visitor team's rank is between 0 and 0
the home team's game number is between 1 and 10
the spread for the home team is between -16.5 and 100
the average wind speed is between 6 and 100 mph
the temperature is between -100 and 66 degrees
the closing total is between 46.5 and 100
$14,724
WON
813-615-11
RECORD
57%
WIN%

Early Unranked Unders is a college football system that identifies value in early-season matchups where neither team is ranked and where offensive expectations are often overstated.

In the first 10 games of the season, unranked teams often lack the consistency and firepower of top programs, leading to sloppy execution, conservative play-calling, and a slower tempo.

The system focuses on regular-season contests where the closing total is above 46, a range that signals scoring potential but often proves inflated when factoring in real game conditions.

Additional filters, such as wind speeds above six MPH and temperatures no higher than 66 degrees, further suppress offensive efficiency, creating an environment where scoring struggles to match market projections.

With the home spread allowed to range widely from slight underdog to heavy favorite, the system captures a broad spectrum of unranked contests where defenses or conditions keep outcomes tighter and lower-scoring than the total suggests, making the under a profitable angle.

Pick: Under 54 (-110, bet365)

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Sam Houston vs Middle Tennessee Betting Trends



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