The UNLV Rebels take on the Wyoming Cowboys in Laramie, Wyoming. Kickoff is set for 7 p.m. ET on CBS Sports Network.
UNLV is favored by 3.5 points on the spread with a moneyline of -170. The total is set at 49.5 points.
Here’s my UNLV vs. Wyoming predictions and college football picks for Saturday, October 4, 2025.
UNLV vs Wyoming Prediction
- UNLV vs. Wyoming Pick: Wyoming +4 or Better
My Wyoming vs. UNLV best bet is on the Pokes to cover. Find the best line available on our live NCAAF odds page.
UNLV vs Wyoming Odds
| UNLV Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3.5 -110 | 49.5 -110o / -110u | -170 |
| Wyoming Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3.5 -110 | 49.5 -110o / -110u | +145 |
- UNLV vs Wyoming point spread: UNLV -3.5
- UNLV vs Wyoming over/under: 49.5 points
- UNLV vs Wyoming moneyline: UNLV -170, Wyoming +145
UNLV vs Wyoming Pick
I've been itching to fade UNLV again for the past two weeks while the Rebels enjoyed their bye week.
No team has a more laughable 4-0 resume than UNLV, which has wins over UCLA, Sam Houston State, Idaho State, and Miami (Ohio). Those four opponents have a combined zero victories against FBS foes.
It's also worth noting that the Rebels were on the verge of being run off the field in Oxford until Miami (Ohio) lost starting quarterback Dequan Finn to an injury on a play where he threw a pick-six.
Still, even with a backup quarterback who isn't capable of running the offense Finn does, the Redhawks found themselves in position to win before fumbling in the red zone in the final minutes of a tie game. It was one of the luckiest wins of the season.
While I don't love this Wyoming team, its offense does have a little more juice this season with quarterback Kaden Anderson. The Pokes, who have played the significantly more difficult schedule, also have found something over their past two games with freshman running back Samuel Harris, who had 19 carries against Colorado after only 18 combined over the first three games. He's averaging 6.9 yards per rush and should have a very productive day against a UNLV defense that struggles to stop the run.
On the season against a clown car schedule, the Rebels' defense ranks outside the top-100 nationally in Rush Success Rate allowed.
Additionally, UNLV has been extremely fortunate on late downs on both sides of the ball. On third downs alone, the Rebels have converted a ridiculous 52% on offense, while holding opponents to just 21%. Despite ranking outside the top 100 nationally in Early Downs EPA, they rank in the top 15 in late down success rate. And on offense, they rank 2nd on late downs despite sitting right around the national average on early downs. They've also enjoyed a +6 turnover margin.
Lastly, Wyoming could benefit from some good old-fashioned fall weather in Laramie against the indoor Rebs. It could be a colder night with some precipitation and wind, which would be much more detrimental to the UNLV offense.
Pick: Wyoming +4 or Better
