Panthers vs. Saints NFL Odds, Picks & Predictions: Sharps, Big Money Experts Targeting Spread

Carolina Panthers vs. New Orleans Saints Odds

The Saints' last-gasp effort at a playoff shot will have to go through the Panthers.

Carolina has lost five straight but will see starter Sam Darnold return from injury. Cam Newton, signed as a free agent, went 0-5 as a starter.

Star running back Christian McCaffrey was ruled out for the season in November.

The Panthers have ranked No. 31 overall in offensive DVOA with their two best offensive players out.

But despite their foibles offensively, their defense is ranked No. 12 overall according to DVOA, a staggering ranking considering how often their offense has put them in horrible positions.

Meanwhile, a Saints win along with a 49ers loss to the Texans and an Eagles loss to the Washington Football Team would launch New Orleans into the No. 6 seed in the NFC.

The Saints will see Taysom Hill come off the COVID list and start. New Orleans was forced to start rookie Ian Book on Monday Night Football last week — to disastrous results. Book threw for just 135 yards with two picks and looked completely hapless out there.

The Saints defense is still among the best in the league, with a No. 4 overall ranking along with the top-ranked rush defense in the NFL.

Sharps and big money bettors are targeting one particular bet for this game — with all the aforementioned factors in mind.

Panthers vs. Saints Sharp Action, Big Money Pick