HomeRight ArrowNHL

Ottawa Senators vs Buffalo Sabres NHL Prediction, Odds, Pick, October 15

Ottawa Senators vs Buffalo Sabres NHL Prediction, Odds, Pick, October 15 article feature image
2 min read
Credit:

Pictured: Alex Lyon. (Credit: Timothy T. Ludwig-Imagn Images)

The Ottawa Senators (1-2-0) and Buffalo Sabres (0-3-0) meet in the NHL tonight. Puck drop is set for 7:00 p.m. EDT at KeyBank Center in Buffalo, N.Y. The game will be broadcast live on ESPN+.

The Senators are favored by -1.5 on the puck line, with the over/under set at 6 (-110o / +110u). The Senators are a -120 favorite to win outright, while the Sabres are -100 to pull off the upset.

Let's get into my Senators vs. Sabres predictions and NHL picks.

Senators vs. Sabres Odds, Pick

Senators Logo
Wednesday, Oct 15
7 p.m. ET
ESPN+
Sabres Logo
Senators Odds
SpreadTotalMoneyline
-1.5
+200
6
-110o / -110u
-120
Sabres Odds
SpreadTotalMoneyline
+1.5
-245
6
-110o / -110u
+100
Odds via bet365. Get up-to-the-minute NHL odds here.
bet365 Logo

Senators vs. Sabres Spread: Senators -1.5 (+200), Sabres +1.5 (-245)

Senators vs. Sabres Over/Under: 6 (-110o / +110u)

Senators vs. Sabres Moneyline: Senators -120, Sabres +100

Header First Logo
Header Second Logo

Senators vs. Sabres Preview

The Senators have started 1–2, giving up six goals to Florida and four more to Nashville. Meanwhile, Buffalo has dropped all three of its games, scoring just five goals total but allowing at least three in each contest.

When two leaky defenses meet, structure often breaks down, and both sides press offensively to mask their own flaws — exactly the kind of environment that leads to overs cashing.

Ottawa will be without captain Brady Tkachuk, who is expected to miss at least four weeks with a hand injury. His absence hurts offensively, but the Senators still have enough forward depth to generate chances against a Sabres team that continues to struggle with defensive zone coverage and goaltending consistency.

Buffalo could get a spark from the return of Zach Benson, with Jordan Greenway and Ukko-Pekka Luukkonen also nearing a comeback. Still, even with reinforcements, the Sabres’ blue line remains thin and prone to breakdowns against fast, transition-heavy teams like Ottawa.


Header First Logo

Senators vs. Sabres Prediction

This game fits perfectly into Evan Abrams’ “Bad Defense Overs” system, which targets matchups between teams that allow over three goals per game and rank near the bottom in defensive efficiency. Through the early season, both Ottawa and Buffalo have struggled to keep pucks out of the net — a formula that tends to create wide-open, high-scoring hockey.

With both clubs ranking near the bottom defensively and showing no signs of tightening up, this matchup checks every box of the Bad Defense Overs system. Expect pace, pressure, and plenty of scoring chances.

NHL Icon
Evan Abrams – Bad Defense Overs
betting on the Over
the game is played during the Regular season
the home team's average number of goals allowed is between 3 and 100
the away team's average number of goals allowed is between 3 and 100
the home team's win percentage is between 0% and 36%
the visitor team's win percentage is between 0% and 36%
$2907
WON
251-211-20
RECORD
54%
WIN%

Best Bet: Over 6 (-110, bet365)

Playbook
Action PRO Upsell Image
Premium picks, tools & analysis
Track & follow smart money
Biggest player prop edges
Real-time expert pick alerts
Author Profile
About the Author

Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.