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Lazio vs. Sassuolo Odds & Betting Predictions - October 27, 2026

Lazio at Sassuolo

5:30 pm

Lazio

8-0-1
6
6 - 2

Sassuolo

2-5-2
2

Lazio at Sassuolo Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Lazio
8-0-1
-0.5
-0.5-108
o2.5-164
-108
Sassuolo
2-5-2
u2.5
+0.5-135
u2.5+130
+265
location pinTuesday 5:30 p.m.
October 27, 2026
Mapei Stadium - Citta del TricoloreReggio Emilia
Lazio vs. Sassuolo Expert Picks
Charlie DiSturco
Charlie DiSturco
Last 30d: 114-216-1 (+7.4u)
Over 3+112
0.5u
Over 3.5+160
0.25u

Prop Odds Comparison

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Line Movement Tracker

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Lazio vs. Sassuolo Public Betting Percentages

Away Logo

Lazio

Public

Home Logo

Sassuolo

92%

Bets%

8%

Money%

Serie A Public Betting Right Arrow

Betting Trends

  • Sassuolo are 0-3 in their last 5 games.
  • Sassuolo are 3-2 in their last 5 games against the spread
  • Sassuolo are 2-3 in their road games against the spread
  • The totals have gone OVER in 3 of Sassuolo' last 5 games
  • The totals have gone OVER in 2 of Sassuolo' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Sassuolo		5-33-02-31-14-2
Lazio		7-13-14-04-13-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Sassuolo		6-22-14-12-04-2
Lazio		5-33-12-23-22-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Sassuolo		2-52-0-10-4-11-11-3-2
Lazio		8-03-0-14-05-02-0-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 24th@COML 0-2+1.5 LU 3.5COM +475
Oct 16th@FROL 2-4+0.5 LO 3.5FRO +167
Oct 11thACMW 1-1+0.5 WU 2.5ACM +292
Sep 18th@MONL 1-2-0.5 LO 2.5MON +150
Sep 13thJUVW 3-2+0.5 WO 2.5SAS +422

Lazio vs. Sassuolo Injury Updates

Lazio Injuries

  • Danilho Doekhi
    DEF

    Doekhi is injured

    Out Indefinitely

  • Gustav Isaksen
    F

    Isaksen is injured with groin

    Out Indefinitely

Sassuolo Injuries

  • Nemanja Matic
    MID

    Calf/Shin Injury

    Out Indefinitely

  • Armand Lauriente
    F

    Back Injury

    Out

  • Ismael Kone
    MID

    Ismaël Koné is expected to return Early November 2026 from Broken ankle.

    Out

See more SERIEA Injuries Right Arrow
Team Stats

13
Fouls
5
15
Shots
7
1
Corners
2
1
Offsides
3
0
Red Cards
1
1
Yellow Cards
1
8
Shots On Goal
2
60%
Possession Time
40%

Goalkeeping

Lazio vs. Sassuolo Odds Comparison

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See more Serie A Odds Right Arrow

Lazio at Sassuolo Team Totals

MatchupOverUnder
Lazio
8-0-1
N/A
N/A
Sassuolo
2-5-2
N/A
N/A