Astros vs. Blue Jays Odds & Betting Predictions - June 22, 2026

Astros at Blue Jays

11:07 pm • SNET
@
Starting Pitchers
pitcherteameraw-l
Shane Bieber logoS.BieberToronto Blue Jays logo0.000-0
Hunter Brown logoH.BrownHouston Astros logo1.101-0

Astros at Blue Jays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
37-42
+1.5
+1.5-205
o7.5+101
+105
Blue Jays
38-39
u7.5
-1.5+169
u7.5-122
-125
location pinMonday 11:07 p.m.
June 22, 2026
Rogers CentreToronto
thermometer image65°Fahrenheit
rain image6%Rain
wind image6Wind
Astros vs. Blue Jays Expert Picks
Brian Bitler
Brian Bitler
Last 30d: 90-90-1 (+29.0u)
HOU +108
3u
Picks Office
Picks Office
Last 30d: 127-127-11 (-9.1u)
TOR -120
1u
Matt Trollo
Matt Trollo
Last 30d: 70-75-8 (-5.7u)
HOU +110
0.5u
(B365) Cease being listed and it seems like lines are based on him instead of Bieber. Brown projects a bit better than Bieber. HOU proj. LU 113/118 wRC+ v RHP/L30, TOR 104/105. Defenses comparable. HOU pen estimators (FIP/xFIP/SIERA) avg 0.82 runs better L30 days. If it's Cease instead of Bieber, this is probably a break even line anyway.

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Blue Jays Public Betting Percentages

Away Logo

Astros

Public

41%

Bets%

59%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Blue Jays
37-4019-2018-2020-2016-20
Astros
37-4219-2218-208-1828-23

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Blue Jays
38-36-321-17-117-19-221-17-216-19-1
Astros
41-34-424-16-117-18-315-1125-22-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Blue Jays
38-3921-1817-2123-1714-22
Astros
37-4220-2117-2111-1525-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 20th@CHCW 8-6+1.5 WO 9TOR +119
Jun 19th@CHCL 2-16+1.5 LO 7CHC +105
Jun 18th@BOSW 4-3+1.5 WU 9.5TOR +120
Jun 17th@BOSW 3-0-1.5 WU 10TOR -105
Jun 16th@BOSW 6-1-1.5 WU 7.5TOR -120

Blue Jays vs. Astros Injury Updates

Blue Jays Injuries

  • Jose Berrios
    SP

    Berrios is out with elbow

    Out

  • Anthony Santander
    RF

    Santander is out with shoulder

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • Bowden Francis
    SP

    Francis is out with shoulder

    Out

  • Addison Barger
    RF

    Addison Barger (elbow) scratched Sunday.

    Out

Astros Injuries

  • Lance McCullers
    SP

    Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.

    Out

Astros vs. Blue Jays Starting Lineups
Astros Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Hunter Brown logoRH.Brown, P1-01.101.04113.22
HITTERSAVGOBPSLGHR
Jeremy Pena logo1J.Pena, SS.283.343.4536
Yordan Alvarez logo2Y.Alvarez, DH.322.428.64025
Christian Walker logo3C.Walker, 1B.241.313.48118
Isaac Paredes logo4I.Paredes, 3B.246.348.41810
Jose Altuve logo5J.Altuve, 2B.235.308.3998
Yainer Diaz logo6Y.Diaz, C.243.265.3512
Cam Smith logo7C.Smith, RF.219.300.3547
Joey Loperfido logo8J.Loperfido, LF.241.344.3290
Jake Meyers logo9J.Meyers, CF.210.269.3283
Blue Jays Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Dylan Cease logoRD.Cease, P4-32.711.19213.56
HITTERSAVGOBPSLGHR
George Springer logo1G.Springer, DH.223.313.3898
Nathan Lukes logo2N.Lukes, LF.306.352.4102
Vladimir Guerrero logo3V.Guerrero, 1B.279.365.3704
Jesus Sanchez logo4J.Sanchez, RF.282.318.4517
Alejandro Kirk logo5A.Kirk, C.200.273.3251
Daulton Varsho logo6D.Varsho, CF.256.329.4196
Kazuma Okamoto logo7K.Okamoto, 3B.229.310.44316
Ernie Clement logo8E.Clement, 2B.292.311.4407
Andres Gimenez logo9A.Gimenez, SS.232.274.3737

Astros vs. Blue Jays Odds Comparison

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Astros at Blue Jays Team Totals

MatchupOverUnder
Astros
37-42
N/A
N/A
Blue Jays
38-39
N/A
N/A