The Toronto Blue Jays host the Houston Astros on June 22, 2026. First pitch from Rogers Centre is scheduled for 7:07 p.m. ET. The game will be broadcast on SNET.
The Blue Jays are favored by -125 on the moneyline and by -1.5 on the run line. The Astros are +105 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Astros vs Blue Jays prediction below, as well as probable pitchers, weather report, and more.
Astros vs Blue Jays Prediction
- Astros vs Blue Jays Pick: Over 7.5 (+105)
My Astros vs Blue Jays best bet is Over 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Blue Jays Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -210 | 7.5 105o / -125u | +105 |
| Blue Jays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +170 | 7.5 105o / -125u | -125 |
- Astros vs Blue Jays moneyline: Astros +105, Blue Jays -125
- Astros vs Blue Jays over/under: 7.5 (-105o / -125u)
- Astros vs Blue Jays spread: Astros +1.5 (-210), Blue Jays -1.5 (+170)
Astros vs Blue Jays Probable Pitchers
| Hunter Brown (RHP, HOU) | Stat | Dylan Cease (RHP, TOR) |
|---|---|---|
| 1-0 | W-L | 4-3 |
| 0.7 | fWAR (FanGraphs) | 2.6 |
| 1.10 / 2.18 | ERA / xERA | 2.71 / 3.04 |
| 1.82 / 2.64 | FIP / xFIP | 2.38 / 2.54 |
| 23.4 | K-BB% | 26.1 |
| 51.6 | GB% | 45.6 |
| .258 | BABIP | .331 |
| 104 | Stuff+ | 108 |
| 97 | Location+ | 98 |
Astros vs Blue Jays MLB Betting Preview, Prediction
Astros starter Hunter Brown goes into Toronto, but we don't know who he'll be squaring off against. It was supposed to be Shane Bieber, but with the PPD yesterday, we're likely to see Dylan Cease start this one.
That hasn't been announced yet, though. Maybe they'll want to keep Bieber on schedule and roll him out there tonight. I doubt it, but I wanted to highlight the possibility. The sportsbooks seem to think it will be Dylan Cease, so that's how we should approach it.
These are the types of speculative lines you can attack. The O/U on this game is set at 7.5, and the over is available at +110 on some sites.
If the Blue Jays announce that Bieber is making this start, that number would likely jump by at least a run, and probably 1.5. Bieber is bad. He walked four and allowed five earned runs on seven hits in his last rehab outing. Last year in the majors, he gave up eight home runs in seven starts (1.8 HR/9).
I think you can bet Over 7.5 and feel like it's a coin flip if Cease starts. If Bieber starts, it's a smash. But the most likely outcome is that Cease gets the ball and we see a quality pitchers' duel between him and Brown.
Hunter Brown returned and threw 92 pitches on June 16, his first start since the very beginning of the year. He generated 12 whiffs, but the command was really off (42.4% Ball%, three walks). I think the Blue Jays can do some damage against him in this start.
I'm going with the over, assuming Cease is starting.
Pick: Over 7.5 (+105, BetMGM)
