Astros vs. Orioles Odds & Betting Predictions - August 21, 2025
Astros at Orioles
11:15 pm • FOXStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 6.24 | 1-7 | ||
![]() | 3.66 | 4-2 |
Astros at Orioles Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Astros 31-39 | -1.5 | -1.5+163 | o8.5-121 | +100 |
Orioles 33-37 | u8.5 | +1.5-198 | u8.5-101 | -120 |

Oriole Park at Camden YardsBaltimore
Astros vs. Orioles Expert Picks
New Owner
Last 30d: 0-0-0 (+0.0u)
HOU +108
2.16u
#bobbyfades
HOU +108
3.24u
#bobbyfades
Wags Wins
Last 30d: 169-208-1 (-65.4u)
BAL -118
1.25u
💰🦡 Jake
Last 30d: 75-82-3 (+0.6u)
Under 0.5 (1st Inn)-110
1.1u
Greg Matherne
Last 30d: 2-9-0 (+0.5u)
Under 9-120
0.6u
Austin Pendergrass
Last 30d: 36-20-1 (+6.6u)
Under 9.5-166
0.3u
Allan Lem
Last 30d: 18-16-1 (+0.0u)
Under 9-117
0.59u
Action Instagram channel best bet, going to tail it
Picks Office
Last 30d: 120-120-9 (-7.6u)
BAL -115
2u
Grant Neiffer
Last 30d: 29-114-4 (+2.3u)
Y.Diaz o0.5 HR+875
4.38u
C.Walker o0.5 HR+650
3.25u
J.Altuve o0.5 HR+900
0.5u

Sean Zerillo
Last 30d: 168-134-11 (+6.3u)
Under 9-108
0.54u
Bet to -125 or 8.5 (-105)
Matt Trollo
Last 30d: 70-66-10 (+0.6u)
BAL -110
1.1u
Pitchers very similar numbers, but BAL much better positioned to exploit Alexander's split (LHBs .344 wOBA, .364 xwOBA) than HOU is to exploit Young's, who nearly no-hit them last time out. HOU offense (16 wRC+ L7 days) and bullpen (worst estimators MLB by nearly half a run L30 days) are both spiraling.
Astros vs. Orioles Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Orioles Public Betting Percentages
Betting Trends
- Orioles are 2-3 in their last 5 games.
- Orioles are 3-2 in their last 5 games against the spread
- Orioles are 13-19 in their road games against the spread
- The totals have gone OVER in 3 of Orioles' last 5 games
- The totals have gone OVER in 20 of Orioles' 38 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Orioles vs. Astros Injury Updates

Orioles Injuries
- Heston KjerstadLF
Kjerstad is out with hamstring
Out
- Jordan Westburg3B
Westburg is out with elbow
Out
- Dylan BeaversRF
Dylan Beavers scratched Tuesday.
Out

Astros Injuries
- Lance McCullersSP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out
Astros vs. Orioles Box Score
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 91 | 5.1 | 3 | 2 | |
![]() | 14 | 1.2 | 2 | 0 | |
![]() | 16 | 1 | 1 | 0 | |
![]() | 20 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 2 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 2 | 1 | 2 |
![]() | 5-5 | 1 | 0 | 1 |
![]() | 1-5 | 1 | 1 | 2 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 1 | 0 | 0 |
![]() | 0-3 | 1 | 0 | 0 |
Orioles Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 84 | 5.1 | 1 | 7 | |
![]() | 37 | 2 | 0 | 0 | |
![]() | 8 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-5 | 0 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 2 |
![]() | 1-3 | 0 | 0 | 0 |
Astros vs. Orioles Odds Comparison
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Astros at Orioles Team Totals
MatchupOverUnder | ||
|---|---|---|
Astros 31-39 | N/A | N/A |
Orioles 33-37 | N/A | N/A |




























