Cubs vs. Pirates Odds & Betting Predictions - September 15, 2025

Cubs at Pirates

10:40 pm • SportsNet PT

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Chicago Cubs

@

Pittsburgh Pirates

pitcher		team	era	w-l
P.Skenes			0.00	0-0
C.Horton			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Cubs 84-63	N/A	N/A	N/A
Pirates 64-84	N/A	N/A	N/A

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Monday 10:40 p.m.

September 15, 2025

PNC ParkPittsburgh

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77°Fahrenheit

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0%Rain

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4Wind

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MLB Public Betting

Pirates are 0-5 in their last 5 games.
Pirates are 2-3 in their last 5 games against the spread
Pirates are 36-37 in their road games against the spread
The totals have gone OVER in 2 of Pirates' last 5 games
The totals have gone OVER in 31 of Pirates' 75 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	81-67	45-30	36-37	17-24	62-42
Cubs	68-79	34-39	34-40	49-57	18-22

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	58-82-8	31-39-5	27-43-3	16-23-2	40-58-6
Cubs	66-73-8	34-35-4	32-38-4	46-54-6	20-18-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	64-84	42-33	22-51	20-21	43-61
Cubs	84-63	45-28	39-35	66-40	17-23

date	opponent	score	spread	over/under	moneyline
Sep 13th	@WSH	W 5-1	-1.5 W	U 9	PIT -115
Sep 12th	@WSH	L 5-6	-1.5 L	O 8.5	WSH -110
Sep 11th	@BAL	L 2-3	+1.5 W	U 8	BAL +105
Sep 10th	@BAL	L 1-2	-1.5 L	U 7	BAL -155
Sep 9th	@BAL	L 2-3	+1.5 W	U 7.5	BAL +125

Johan Oviedo
SP
Oviedo is questionable with elbow
Questionable

Endy Rodriguez
1B
Rodriguez is out with elbow
Out
Jared Jones
SP
Jones is out with elbow
Out

Michael Soroka
SP
Soroka is out with shoulder
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

See more MLB Injuries

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MatchupOverUnder
Cubs 84-63	N/A	N/A
Pirates 64-84	N/A	N/A